Research groups
| Molecular Biology of Breast Cancer | Cancer genome variation |
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| Headed by Group Leader and Professor Anne-Lise Børresen-Dale |
Headed by Group Leader and Professor Vessela N. Kristensen |
Project groups
| Molecular portraits of breast cancer: Translating genomics to the clinical practice | Molecular signatures of disseminated tumor cells in breast cancer | Statistical integrated approaches | Response and Side Effects of Cancer Therapy |
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| Therese Sørlie | Lars O. Baumbusch | Hiroko K. Solvang | Hege Edvardsen |
| Molecular Studies of Ovarian Carcinoma | Cancer in the respiratory tract | Breast cancer genomics | Somatic genetics of breast cancer |
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| Åslaug Helland | Odd Terje Brustugun |
Kristine Kleivi | Anita Langerød |
Our goal is to follow the linear time course of predisposition, initiation, early stages and advanced disease and to dissect the molecular mechanisms triggered at each stage and to follow the multidimentional interactions at various levels in a systems biology approach to be able to better do risk estimation, prognostication and prediction.
To reach these goals we have divided our research into 7 activities:
- Gene environment interaction in breast cancer risk
- Tumor initiation and early diagnosis
- Tumor progression and metastasis
- Prediction of treatment response and targeted therapy
- Integrated approaches
- Functional validation
- Biostatistical challenges and approaches
![]() | Anne-Lise Børresen-Dale is chair of the 21st biennial Meeting of the EACR, which is held Oslo, Norway, 26-29 June, 2010. Conference web page - click here. |
Contact information:
Department of Genetics, Institute for Cancer Research
The Norwegian Radium Hospital, N-0310 Oslo, Norway
Phone: +47 22 93 56 77, Fax: +47 22 93 44 40, Switchboard: +47 22 93 40 00
Research coordinator: Gry A. Geitvik
Department secretary: Mona Hagen
Jun 30, 2010
Latest publications
Department of Genetics
Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations
Eur J Clin Pharmacol (in press)
PubMed 20665013
Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
Mol Oncol (in press)
PubMed 20663721
The genetics and epigenetics of fatigue
PM R, 2 (5), 456-65
PubMed 20656628














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