PubMed registered articles
Department of Biochemistry, from 1971 and onwards
Publications published since 1971 or in press from Department of Biochemistry
726 publications found
Publications in press
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Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein
Blood (in press)
PubMed 20574048 -
Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells
Cell Microbiol (in press)
PubMed 19159389 -
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2) (in press)
PubMed 18204305 -
Endocytosis and retrograde transport of Shiga toxin
Toxicon (in press)
PubMed 19951719 -
New metal-based nanoparticles for intravenous use: requirements for clinical success with focus on medical imaging
Nanomedicine (in press)
PubMed 20570639 -
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res (in press)
PubMed 20643123
Publications 2010
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Protein secretion: unconventional exit by exophagy
Curr Biol, 20 (9), R415-8
PubMed 20462486 -
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
Autophagy, 6 (3), 330-44
PubMed 20168092 -
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy
Mol Cell, 38 (2), 265-79
PubMed 20417604 -
An inhibitory role of the G-protein regulator AGS3 in mTOR-dependent macroautophagy
PLoS One, 5 (1), e8877
PubMed 20126274 -
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
PubMed 20451383 -
Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
J Infect Dis, 201 (5), 783-92
PubMed 20121435 -
Sialic acid-binding dwarf elder four-chain lectin displays nucleic acid N-glycosidase activity
Biochimie, 92 (1), 71-80
PubMed 19799962 -
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
PubMed 20643357 -
Autophagy and its physiological relevance in arthropods Current knowledge and perspectives
Autophagy, 6 (5), 575-588 -
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end-directed vesicle transport
J Cell Biol, 188 (2), 253-69
PubMed 20100911 -
Interplay between toxin transport and flotillin localization
PLoS One, 5 (1), e8844
PubMed 20107503 -
ESCRT & Co
Biol Cell, 102 (5), 293-318
PubMed 20222872 -
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
PubMed 20190829 -
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
PubMed 20208530 -
Cytokinesis and cancer
FEBS Lett, 584 (12), 2652-61
PubMed 20371245 -
Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine
FEBS Lett, 584 (12), 2626-34
PubMed 20385131 -
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
EMBO J, 29 (14), 2421-32
PubMed 20551902 -
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
PubMed 19830447
Publications 2009
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Monitoring autophagic degradation of p62/SQSTM1
Methods Enzymol, 452, 181-97
PubMed 19200883 -
Autophagy in tumour suppression and promotion
Mol Oncol, 3 (4), 366-75
PubMed 19559660 -
Sorting nexin 8 regulates endosome-to-Golgi transport
Biochem Biophys Res Commun, 390 (1), 109-14
PubMed 19782049 -
Ligand-specific induction of endocytosis in taste receptor cells
J Exp Biol, 212 (Pt 1), 42-9
PubMed 19088209 -
Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly
J Leukoc Biol, 85 (3), 469-80
PubMed 19112091 -
Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101
J Cell Sci, 122 (Pt 21), 3883-93
PubMed 19808888 -
ESCRTing membrane deformation
Cell, 136 (1), 15-7
PubMed 19135881 -
Cell death during Drosophila melanogaster early oogenesis is mediated through autophagy
Autophagy, 5 (3), 298-302
PubMed 19066465 -
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
PubMed 19325624 -
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
PubMed 19194501 -
The role of ESCRT proteins in attenuation of cell signalling
Biochem Soc Trans, 37 (Pt 1), 137-42
PubMed 19143618 -
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
PubMed 19619532 -
How do ESCRT proteins control autophagy?
J Cell Sci, 122 (Pt 13), 2179-83
PubMed 19535733 -
Glycosphingolipid requirements for endosome-to-Golgi transport of Shiga toxin
Traffic, 10 (7), 868-82
PubMed 19453975 -
SNX4 in complex with clathrin and dynein: implications for endosome movement
PLoS One, 4 (6), e5935
PubMed 19529763 -
beta-arrestins attenuate p38 mediated endosome to Golgi transport
Cell Microbiol, 11 (5), 796-807
PubMed 19159388 -
Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
PubMed 19702012 -
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
PubMed 19603039 -
ESCRT proteins in physiology and disease
Exp Cell Res, 315 (9), 1619-26
PubMed 19013455 -
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
PubMed 19490536 -
Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants
J Cell Sci, 122 (Pt 14), 2413-23
PubMed 19571114 -
Characterization of clathrin and Syk interaction upon Shiga toxin binding
Cell Signal, 21 (7), 1161-8
PubMed 19289168 -
Increased protein stability of FGF1 can compensate for its reduced affinity for heparin
J Biol Chem, 284 (37), 25388-403
PubMed 19574212 -
Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane
Biochemistry, 48 (30), 7209-18
PubMed 19558187 -
The adaptor protein p62/SQSTM1 targets invading bacteria to the autophagy pathway
J Immunol, 183 (9), 5909-16
PubMed 19812211
Publications 2008
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Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1
EMBO Rep, 9 (2), 171-8
PubMed 18188183 -
Quantitative analysis of autophagic activity in Drosophila neural tissues by measuring the turnover rates of pathway substrates
Methods Enzymol, 451, 639-51
PubMed 19185743 -
SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome
Am J Hum Genet, 82 (4), 1003-10
PubMed 18342287 -
Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis
Mol Biol Cell, 19 (8), 3390-403
PubMed 18480409 -
ADP-ribosylation of actin by the Clostridium botulinum C2 toxin in mammalian cells results in delayed caspase-dependent apoptotic cell death
Infect Immun, 76 (10), 4600-8
PubMed 18710868 -
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Autophagy, 4 (2), 151-75
PubMed 18188003 -
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
Autophagy, 4 (4), 500-6
PubMed 18326940 -
Mechanisms and functions of endocytosis
J Cell Biol, 180 (1), 7-11
PubMed 18195098 -
Regulation of early endosomal entry by the Drosophila tumor suppressors Rabenosyn and Vps45
Mol Biol Cell, 19 (10), 4167-76
PubMed 18685079 -
Monitoring autophagy in insect eggs
Methods Enzymol, 451, 669-83
PubMed 19185745 -
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
J Cell Biol, 180 (6), 1065-71
PubMed 18347073 -
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
PubMed 18031739 -
Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
PubMed 18588977 -
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236 -
ESCRT functions in autophagy and associated disease
Cell Cycle, 7 (9), 1166-72
PubMed 18418046 -
Clathrin-independent endocytosis: from nonexisting to an extreme degree of complexity
Histochem Cell Biol, 129 (3), 267-76
PubMed 18193449 -
Cell biology: Viruses in camouflage
Nature, 453 (7194), 466-7
PubMed 18497813 -
Self-eating from an ER-associated cup
J Cell Biol, 182 (4), 621-2
PubMed 18725534 -
Phosphorylation of fibroblast growth factor (FGF) receptor 1 at Ser777 by p38 mitogen-activated protein kinase regulates translocation of exogenous FGF1 to the cytosol and nucleus
Mol Cell Biol, 28 (12), 4129-41
PubMed 18411303 -
Cellular trafficking of quantum dot-ligand bioconjugates and their induction of changes in normal routing of unconjugated ligands
Nano Lett, 8 (7), 1858-65
PubMed 18570482 -
Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation
Mol Biol Cell, 19 (8), 3454-62
PubMed 18508924 -
The Mitogen-activated protein kinase p38 links Shiga Toxin-dependent signaling and trafficking
Mol Biol Cell, 19 (1), 95-104
PubMed 17959827 -
FGF-1: from biology through engineering to potential medical applications
Crit Rev Clin Lab Sci, 45 (1), 91-135
PubMed 18293181
Publications 2007
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The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis
Exp Cell Res, 313 (8), 1696-709
PubMed 17382318 -
Fibroblast growth factor receptor-induced phosphorylation of STAT1 at the Golgi apparatus without translocation to the nucleus
J Cell Physiol, 212 (1), 148-56
PubMed 17311277 -
Endocytosis of the dermatan sulfate proteoglycan decorin utilizes multiple pathways and is modulated by epidermal growth factor receptor signaling
Biochimie, 89 (5), 637-57
PubMed 17335953 -
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
PubMed 17984323 -
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
PubMed 17956217 -
Origin and evolution of self-consumption: autophagy
Adv Exp Med Biol, 607, 111-8
PubMed 17977463 -
Structural requirements for furin-induced cleavage and activation of Shiga toxin
Biochem Biophys Res Commun, 357 (1), 144-9
PubMed 17407762 -
Cholesterol regulates prostasome release from secretory lysosomes in PC-3 human prostate cancer cells
Eur J Cell Biol, 86 (7), 405-15
PubMed 17601634 -
ESCRTs
Curr Biol, 17 (2), R42-3
PubMed 17240322 -
Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation
Traffic, 8 (11), 1617-29
PubMed 17714434 -
Productive entry of type C foot-and-mouth disease virus into susceptible cultured cells requires clathrin and is dependent on the presence of plasma membrane cholesterol
Virology, 369 (1), 105-18
PubMed 17714753 -
A nuclear export sequence located on a beta-strand in fibroblast growth factor-1
J Biol Chem, 282 (36), 26245-56
PubMed 17616529 -
Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films
J Struct Biol, 158 (3), 386-400
PubMed 17287132 -
p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy
J Biol Chem, 282 (33), 24131-45
PubMed 17580304 -
RILP is required for the proper morphology and function of late endosomes
J Cell Sci, 120 (Pt 21), 3729-37
PubMed 17959629 -
GASA4, one of the 14-member Arabidopsis GASA family of small polypeptides, regulates flowering and seed development
Plant Cell Physiol, 48 (3), 471-83
PubMed 17284469 -
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
PubMed 17268460 -
ESCRTs and Fab1 regulate distinct steps of autophagy
Curr Biol, 17 (20), 1817-25
PubMed 17935992 -
Linking lysosomal trafficking defects with changes in aging and stress response in Drosophila
Autophagy, 3 (5), 499-501
PubMed 17617737 -
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
Genetics, 176 (2), 1283-97
PubMed 17435236 -
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
PubMed 17510644 -
Phosphoinositide-regulated retrograde transport of ricin: crosstalk between hVps34 and sorting nexins
Traffic, 8 (3), 297-309
PubMed 17319803 -
Polyunsaturated fatty acids regulate Shiga toxin transport
Biochem Biophys Res Commun, 364 (2), 283-8
PubMed 17942073 -
Protein kinase Cdelta is activated by Shiga toxin and regulates its transport
J Biol Chem, 282 (22), 16317-28
PubMed 17403690 -
SNX1 and SNX2 mediate retrograde transport of Shiga toxin
Biochem Biophys Res Commun, 358 (2), 566-70
PubMed 17498660 -
Indirubin-3'-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
Oncogene, 26 (44), 6372-85
PubMed 17533378
Publications 2006
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The function of ubiquitin-binding protein complexes in endocytic downregulation of growth factor receptors
Crit Rev Oncog, 12 (3-4), 301; discussion 301-2
PubMed 17425510 -
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
PubMed 16554368 -
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
PubMed 16448788 -
Depletion of sphingolipids facilitates endosome to Golgi transport of ricin
Traffic, 7 (9), 1243-53
PubMed 16919154 -
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
PubMed 17077855 -
Specification of SUMO1- and SUMO2-interacting motifs
J Biol Chem, 281 (23), 16117-27
PubMed 16524884 -
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
PubMed 16462748 -
Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain
Nat Struct Mol Biol, 13 (11), 1031-2
PubMed 17057714 -
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
PubMed 16429130 -
Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA
Biochim Biophys Acta, 1763 (11), 1325-34
PubMed 17045350 -
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
EMBO J, 25 (4), 683-92
PubMed 16467847 -
Transcriptional targeting of small interfering RNAs into cancer cells
Biochem Biophys Res Commun, 350 (4), 854-9
PubMed 17034763 -
Reduced binding of FGF1 to mutant fibroblast growth factor receptor 3
Growth Factors, 24 (2), 111-9
PubMed 16801131 -
Shiga toxin regulates its entry in a Syk-dependent manner
Mol Biol Cell, 17 (3), 1096-109
PubMed 16371508 -
Endocytic processing of connexin43 gap junctions: a morphological study
Biochem J, 393 (Pt 1), 59-67
PubMed 16162097 -
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
PubMed 16600212 -
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
PubMed 16874068 -
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
PubMed 16467569 -
FGF-1 as a possible carrier for targeted drug delivery
Oncol Res, 16 (1), 27-34
PubMed 16783965 -
A mutant human IgG molecule with only one C1q binding site can activate complement and induce lysis of target cells
Eur J Immunol, 36 (1), 129-38
PubMed 16323243 -
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
PubMed 16859684 -
Hrs makes receptors silent: a key to endosomal protein sorting
Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
PubMed 17425508 -
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
PubMed 16901703 -
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
PubMed 16720641 -
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
PubMed 16837550 -
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
PubMed 16554828 -
The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
J Cell Sci, 119 (Pt 19), 3944-57
PubMed 16954148 -
Assessing invasion criteria in fine needle aspirates from breast carcinoma diagnosed as DICS or invasive carcinoma: can we identify an invasive component in addition to DCIS?
Acta Cytol, 50 (3), 263-70
PubMed 16780019 -
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
PubMed 16888620 -
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
PubMed 16716591 -
EDEM is involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol
Mol Biol Cell, 17 (4), 1664-75
PubMed 16452630 -
Thymidine secretion by hybridoma and myeloma cells
Biochem Biophys Res Commun, 342 (1), 221-6
PubMed 16472778 -
Functional diversity of FGF-2 isoforms by intracellular sorting
Bioessays, 28 (5), 504-14
PubMed 16615083 -
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
PubMed 17003104 -
Transport of ricin from endosomes to the Golgi apparatus is regulated by Rab6A and Rab6A'
Traffic, 7 (6), 663-72
PubMed 16683916 -
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
J Biol Chem, 281 (16), 11405-12
PubMed 16495214 -
Structural requirements of FGF-1 for receptor binding and translocation into cells
Biochemistry, 45 (51), 15338-48
PubMed 17176056
Publications 2005
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Design, implementation, and evaluation of the Resilient Smalltalk embedded platform
Comput. Lang. Syst. Struct., 31 (3-4), 127-141 -
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
J Cell Biol, 171 (4), 603-14
PubMed 16286508 -
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
PubMed 15914539 -
Identification of human and rat FAD-AMP lyase (cyclic FMN forming) as ATP-dependent dihydroxyacetone kinases
Biochem Biophys Res Commun, 338 (4), 1682-9
PubMed 16289032 -
Fluorimetric HPLC detection of endogenous riboflavin 4',5'-cyclic phosphate in rat liver at nanomolar concentrations
Anal Biochem, 341 (2), 214-9
PubMed 15907866 -
When and from whom do female pied flycatchers (Ficedula hypoleuca) solicit copulations
Behaviour, 142, 1059-1076 -
Recent developments in administrative law - Public controversy over peer review
Adm. Law Rev., 57 (1), 275-284 -
Golgi vesiculation induced by cholesterol occurs by a dynamin- and cPLA2-dependent mechanism
Traffic, 6 (2), 144-56
PubMed 15634214 -
Cellular internalization of cytolethal distending toxin: a new end to a known pathway
Cell Microbiol, 7 (7), 921-34
PubMed 15953025 -
Ubiquitylation and cell signaling
EMBO J, 24 (19), 3353-9
PubMed 16148945 -
Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation
EMBO Rep, 6 (7), 635-41
PubMed 15962011 -
Different intracellular trafficking of FGF1 endocytosed by the four homologous FGF receptors
J Cell Sci, 118 (Pt 17), 3869-81
PubMed 16091423 -
The disulfide isomerase Grp58 is a protective factor against prion neurotoxicity
J Neurosci, 25 (11), 2793-802
PubMed 15772339 -
Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B
Cell, 121 (3), 437-50
PubMed 15882625 -
Caveolae: stable membrane domains with a potential for internalization
Traffic, 6 (9), 720-4
PubMed 16101676 -
[Ricin--a therapeutic agent and a biological weapon]
Tidsskr Nor Laegeforen, 125 (18), 2477-9
PubMed 16186864 -
Manipulation of male quality in wild tits: effects on paternity loss
Behav. Ecol., 16 (4), 747-754 -
The Rab5 effector Rabaptin-5 and its isoform Rabaptin-5delta differ in their ability to interact with the small GTPase Rab4
FEBS J, 272 (1), 37-46
PubMed 15634330 -
Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction
FEBS Lett, 579 (1), 203-6
PubMed 15620714 -
Presence of multiple sites containing polar material in spherical Escherichia coli cells that lack MreB
J Bacteriol, 187 (17), 6187-96
PubMed 16109960 -
Delivery into cells: lessons learned from plant and bacterial toxins
Gene Ther, 12 (11), 865-72
PubMed 15815697 -
EGFR gene copy number heterogeneity in fine-needle aspiration cytology from breast carcinomas determined by chromogenic in situ hybridization
Diagn Cytopathol, 33 (4), 228-32
PubMed 16138375 -
Cytologic features of ductal carcinoma in situ in fine-needle aspiration of the breast mirror the histopathologic growth pattern heterogeneity and grading
Cancer, 105 (1), 21-7
PubMed 15593325 -
Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
Methods Mol Biol, 309, 83-91
PubMed 15990399 -
In memoriam: Svein Haftorn, 1925-2003
AUK, 122 (1), 358 -
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
PubMed 15755741 -
Diphtheria toxin translocation across cellular membranes is regulated by sphingolipids
Biochem Biophys Res Commun, 329 (2), 465-73
PubMed 15737610 -
Reconstitution of active diphtheria toxin based on a hexahistidine tagged version of the B-fragment produced to high yields in bacteria
Toxicon, 46 (8), 900-6
PubMed 16260019 -
Individual fluctuating asymmetry in pied flycatchers (Ficedula hypoleuca) persists across moults, but is not heritable and not related to fitness
Evol. Ecol. Res., 7 (3), 381-406 -
The A-subunit of surface-bound Shiga toxin stimulates clathrin-dependent uptake of the toxin
FEBS J, 272 (16), 4103-13
PubMed 16098193 -
Actin-based motility of endosomes is linked to the polar tip growth of root hairs
Eur J Cell Biol, 84 (6), 609-21
PubMed 16032929 -
Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
Biochemistry, 44 (16), 6071-80
PubMed 15835896 -
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
Mol Biol Cell, 16 (2), 794-810
PubMed 15574884 -
Highly stable mutants of human fibroblast growth factor-1 exhibit prolonged biological action
J Mol Biol, 352 (4), 860-75
PubMed 16126225
Publications 2004
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The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
PubMed 15240819 -
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
PubMed 15229652 -
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
PubMed 14594215 -
[Impaired cerebral autoregulation in asymptomatic patients with carotid artery stenosis: comparison of acetazolamide-SPECT and transcranial CO(2)-dopplersonography]
Zentralbl Chir, 129 (3), 178-82
PubMed 15237321 -
The biogenesis of multivesicular endosomes
Nat Rev Mol Cell Biol, 5 (4), 317-23
PubMed 15071556 -
Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites
J Cell Sci, 117 (Pt 12), 2557-68
PubMed 15128873 -
Early learning affects social dominance: interspecifically cross-fostered tits become subdominant
Behav. Ecol., 15 (2), 262-268 -
ERK2 prohibits apoptosis-induced subcellular translocation of orphan nuclear receptor NGFI-B/TR3
J Biol Chem, 279 (48), 50097-101
PubMed 15448159 -
Trafficking and signaling pathways of nuclear localizing protein ligands and their receptors
Bioessays, 26 (9), 993-1004
PubMed 15351969 -
Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L) (vol 271, pg 2350, 2004)
Eur. J. Biochem., 271 (13), 2853 -
Cloning and characterization of the genes encoding toxic lectins in mistletoe (Viscum album L)
Eur J Biochem, 271 (12), 2350-60
PubMed 15182350 -
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases
J Biol Chem, 279 (31), 32786-95
PubMed 15159412 -
Efficient endosome-to-Golgi transport of Shiga toxin is dependent on dynamin and clathrin
J Cell Sci, 117 (Pt 11), 2321-31
PubMed 15126632 -
Caveolin-1 and MAL are located on prostasomes secreted by the prostate cancer PC-3 cell line
J Cell Sci, 117 (Pt 22), 5343-51
PubMed 15466889 -
Translocation of FGF-1 and FGF-2 across vesicular membranes occurs during G1-phase by a common mechanism
Mol Biol Cell, 15 (2), 801-14
PubMed 14657241 -
Branching sites and morphological abnormalities behave as ectopic poles in shape-defective Escherichia coli
Mol Microbiol, 52 (4), 1045-54
PubMed 15130123 -
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
PubMed 14604990 -
The history of ricin, abrin and related toxins
Toxicon, 44 (4), 361-70
PubMed 15302520 -
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
PubMed 15296715 -
Pathways followed by protein toxins into cells
Int J Med Microbiol, 293 (7-8), 483-90
PubMed 15149022 -
Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes
J Cell Biol, 164 (6), 923-33
PubMed 15007060 -
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
PubMed 15292400 -
Cross-fostering of pied flycatchers (Ficedula hypoleuca) to heterospecific hosts in the wild: A study of sexual imprinting
Behaviour, 141, 1079-1102 -
The structure of an endosomal protein sorter
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Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
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Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
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The expression problem revisited - Four new solutions using generics
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Acquisition of Hrs, an essential component of phagosomal maturation, is impaired by mycobacteria
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Design of fully active FGF-1 variants with increased stability
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Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
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STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
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Endosome-to-Golgi transport is regulated by protein kinase A type II alpha
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Look AHEAD (Action for Health in Diabetes): design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes
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Cytotoxic activity of 6-alkynyl- and 6-alkenylpurines
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IL-7 receptor is present on human microvascular endothelial cells
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Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
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Endocytosis and signaling: a relationship under development
Cell, 115 (5), 513-21
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MHC class II loading of high or low affinity peptides directed by Ii/peptide fusion constructs: implications for T cell activation
Int Immunol, 15 (11), 1291-9
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The cytoplasmic tail of invariant chain modulates antigen processing and presentation
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Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
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Thermal depolymerization of alginate in the solid state
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Clathrin-coated pits with long, dynamin-wrapped necks upon expression of a clathrin antisense RNA
Proc Natl Acad Sci U S A, 100 (9), 5175-80
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Characterization and tissue expression of acidic fibroblast growth factor binding protein homologue in Drosophila melanogaster
Gene, 310, 185-91
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Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
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Field experiments on biological control of fire blight by bacterial antagonists
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Induction of direct endosome to endoplasmic reticulum transport in Chinese hamster ovary (CHO) cells (LdlF) with a temperature-sensitive defect in epsilon-coatomer protein (epsilon-COP)
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The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
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Phosphatidylinositol-3 kinase-dependent activation of Akt does not correlate with either high mitogenicity or cell migration induced by FGF-1
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Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
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PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
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Isolation and characterization of a new d-galactose-binding lectin from Sambucus racemosa L
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Phosphorylation of insulin-like growth factor binding protein-3 by deoxyribonucleic acid-dependent protein kinase reduces ligand binding and enhances nuclear accumulation
Endocrinology, 144 (5), 1984-93
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High molecular weight DNA fragments are processed by caspase sensitive or caspase independent pathways in cultures of cerebellar granule neurons
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Role of lipids in the retrograde pathway of ricin intoxication
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Role of lipids in the retrograde pathway of ricin intoxication
Traffic, 4 (8), 544-52
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Time resolved spectroscopic optical coherence tomography for diffusion measurements
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Differential role of actin, clathrin, and dynamin in Fc gamma receptor-mediated endocytosis and phagocytosis
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Caveolae: anchored, multifunctional platforms in the lipid ocean
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Cholesterol loading induces a block in the exit of VSVG from the TGN
Traffic, 4 (11), 772-84
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Publications 2002
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Cytotoxic and antibacterial activity of 2-oxopurine derivatives
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Phosphorylation of Hrs downstream of the epidermal growth factor receptor
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The small GTPase Rab22 interacts with EEA1 and controls endosomal membrane trafficking
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Selective regulation of the Rab9-independent transport of ricin to the Golgi apparatus by calcium
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The cytoplasmic tail of invariant chain regulates endosome fusion and morphology
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Early endosomal regulation of Smad-dependent signaling in endothelial cells
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Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor
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Publications 2001
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Modulation of intracellular transport of acidic fibroblast growth factor by mutations in the cytoplasmic receptor domain
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An interaction between ricin and calreticulin that may have implications for toxin trafficking
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Ability of the Tat basic domain and VP22 to mediate cell binding, but not membrane translocation of the diphtheria toxin A-fragment
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Reconstitution of clathrin-independent endocytosis at the apical domain of permeabilized MDCK II cells: requirement for a Rho-family GTPase
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Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
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Phosphoinositides and phagocytosis
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Cell biology. A lipid oils the endocytosis machine
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Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases
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Wortmannin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells
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Wortmanin-sensitive trafficking steps in the endocytic pathway in rat liver endothelial cells
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[Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
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Endovascular treatment of type B aortic dissections
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Evading apoptosis by calcitriol-differentiated human leukemic HL-60 cells is not mediated by changes in CD95 receptor system but by increased sensitivity of these cells to insulin
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Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
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Ricin
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Microbiology. Fighting anthrax with a mutant toxin
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A PtdIns(3)P-specific probe cycles on and off host cell membranes during Salmonella invasion of mammalian cells
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Hrs recruits clathrin to early endosomes
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Function of Hrs in endocytic trafficking and signalling
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FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
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Shiga toxins
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In vivo documentation of photochemical internalization, a novel approach to site specific cancer therapy
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PX domains: attracted by phosphoinositides
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The role of phosphoinositides in membrane transport
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DNA binding-independent transcriptional activation by the androgen receptor through triggering of coactivators
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Trafficking of lipids - Introduction
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Introduction. Trafficking of lipids
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Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
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The Rab GTPase family
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The Rab GTPase family
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Publications 2000
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Regulation and intracellular trafficking pathways of the endothelin receptors
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Reduced [3H]IP3 binding but unchanged IP3 receptor levels in the rat hippocampus CA1 region following transient global ischemia and tolerance induction
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Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages
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Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
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Initial events in infectious salmon anemia virus infection: evidence for the requirement of a low-pH step
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Design of toxins that can be activated by cell-specific proteases and their potential use in targeted cell killing
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Requirement for prolonged action in the cytosol for optimal protein synthesis inhibition by diphtheria toxin
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Penetration of protein toxins into cells
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Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy
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Autophagosome-associated variant isoforms of cytosolic enzymes
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Interaction of the EEA1 FYVE finger with phosphatidylinositol 3-phosphate and early endosomes. Role of conserved residues
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Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
EMBO J, 19 (17), 4577-88
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Endosome to Golgi transport of ricin is regulated by cholesterol
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Requirement for C-terminal end of fibroblast growth factor receptor 4 in translocation of acidic fibroblast growth factor to cytosol and nucleus
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Requirement of phosphatidylinositol 3-kinase activity for translocation of exogenous aFGF to the cytosol and nucleus
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Organization, chromosomal localization and promoter analysis of the gene encoding human acidic fibroblast growth factor intracellular binding protein
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Apical endocytosis of ricin in MDCK cells is regulated by the cyclooxygenase pathway
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Fc receptor mediated endocytosis of small soluble immunoglobulin G immune complexes in Kupffer and endothelial cells from rat liver
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Role for dynamin in late endosome dynamics and trafficking of the cation-independent mannose 6-phosphate receptor
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Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin
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Commentary - Probing pores with peptide plugs: Topology of membrane-inserted diphtheria toxin
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Oral presentations in science and medicine. An art in decline?
Anticancer Res, 20 (5A), 2795-9
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Palaeoecological investigations towards the reconstruction of the history of forest clearances and coastal heathlands in south-western Norway
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Ricin transport into cells: studies of endocytosis and intracellular transport
Int J Med Microbiol, 290 (4-5), 415-20
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Apical macropinocytosis in polarized MDCK cells: regulation by N-ethylmaleimide-sensitive proteins
Eur J Cell Biol, 79 (7), 447-57
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Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives
EMBO J, 19 (22), 5943-50
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Release of gelonin from endosomes and lysosomes to cytosol by photochemical internalization
Biochim Biophys Acta, 1475 (3), 307-13
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Photochemical internalisation increases the cytotoxic effect of the immunotoxin MOC31-gelonin
Int J Cancer, 87 (6), 853-9
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Detection of high molecular weight DNA fragments characteristic of early stage apoptosis in cerebellar granule cells exposed to glutamate
Exp Brain Res, 135 (2), 173-8
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Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors
Mol Endocrinol, 14 (10), 1603-17
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Secretion of thymidine by hybridoma cells
Adv Exp Med Biol, 486, 295-301
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Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer
Exp Cell Res, 261 (1), 111-8
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Cycling lipids
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Membrane traffic: Cycling lipids
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Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate
Mol Cell Biol, 20 (20), 7685-92
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Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
Biochemistry, 39 (49), 15091-100
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Publications 1999
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Photochemical internalization: a novel technology for delivery of macromolecules into cytosol
Cancer Res, 59 (6), 1180-3
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Biocontrol of fire blight with bacterial antagonists
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Direct interaction of EEA1 with Rab5b
Eur J Biochem, 265 (1), 361-6
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The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
Biochem J, 338 ( Pt 2), 539-43
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Uptake and intracellular transport of acidic fibroblast growth factor: evidence for free and cytoskeleton-anchored fibroblast growth factor receptors
Mol Biol Cell, 10 (11), 3835-48
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Phosphoinositides in membrane traffic
Curr Opin Cell Biol, 11 (4), 460-5
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Toxins that are activated by HIV type-1 protease through removal of a signal for degradation by the N-end-rule pathway
Biochem J, 343 Pt 1, 199-207
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Regulation of endocytic membrane traffic by phosphatidylinositol 3-phosphate
Biochem Soc Trans, 27 (4), 666-70
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FYVE finger proteins as effectors of phosphatidylinositol 3-phosphate
Chem Phys Lipids, 98 (1-2), 87-94
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Epidemiology of Diabetes Interventions and Complications (EDIC): Design, implementation, and preliminary results of a long-term follow-up of the Diabetes Control and Complications Trial cohort
Diabetes Care, 22 (1), 99-111 -
Hepatocyte growth factor (HGF) induces interleukin-11 secretion from osteoblasts: a possible role for HGF in myeloma-associated osteolytic bone disease
Blood, 94 (11), 3883-8
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Effects of mutations of a phosphorylation site in an exposed loop in acidic fibroblast growth factor
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Nathaniel Pigott and Edward Pigott, itinerant astronomers
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[The Nobel Prize in physiology and medicine]
Tidsskr Nor Laegeforen, 119 (30), 4450
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Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles
Mol Biol Cell, 10 (4), 961-74
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Endocytosis and intracellular transport of ricin: recent discoveries
FEBS Lett, 452 (1-2), 67-70
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The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
PubMed 10506127 -
Polarized transport of MHC class II molecules in Madin-Darby canine kidney cells is directed by a leucine-based signal in the cytoplasmic tail of the beta-chain
J Immunol, 163 (5), 2540-8
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Endocytic mechanisms responsible for uptake of GPI-linked diphtheria toxin receptor
J Cell Sci, 112 ( Pt 22), 3899-909
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FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
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Fluid phase endocytosis and galactosyl receptor-mediated endocytosis employ different early endosomes
Biochim Biophys Acta, 1421 (2), 317-28
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Unifying genericity - Combining the benefits of virtual types and parameterized classes
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Urokinase-type plasminogen activator receptor is internalized by different mechanisms in polarized and nonpolarized Madin-Darby canine kidney epithelial cells
Mol Biol Cell, 10 (1), 179-95
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Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
J Biol Chem, 274 (48), 34443-9
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[Activation of the cell proliferation program by acidic fibroblast growth factor (aFGF)]
Postepy Hig Med Dosw, 53 (2), 277-89
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Following angiogenin during angiogenesis: a journey from the cell surface to the nucleolus
Arch Immunol Ther Exp (Warsz), 47 (5), 299-305
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Publications 1998
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Endocytosed ricin and asialoorosomucoid follow different intracellular pathways in hepatocytes
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Phacoemulsification in eyes with pseudoexfoliation
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Modulation of the intracellular stability and toxicity of diphtheria toxin through degradation by the N-end rule pathway
EMBO J, 17 (2), 615-25
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CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1
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FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
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Two distinct effectors of the small GTPase Rab5 cooperate in endocytic membrane fusion
EMBO J, 17 (7), 1930-40
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Inability of the acidic fibroblast growth factor mutant K132E to stimulate DNA synthesis after translocation into cells
J Biol Chem, 273 (18), 11164-72
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Cloning of an intracellular protein that binds selectively to mitogenic acidic fibroblast growth factor
Biochem J, 336 ( Pt 1), 213-22
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Expression of mutant dynamin inhibits toxicity and transport of endocytosed ricin to the Golgi apparatus
J Cell Biol, 140 (3), 553-63
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Transport of apically but not basolaterally internalized ricin to the Golgi apparatus is stimulated by 8-Br-cAMP in MDCK cells
FEBS Lett, 431 (2), 200-4
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Variation in the proregion structure of heparin-binding EGF-like growth factor precursors
Gene, 212 (1), 1-4
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Evidence that phosphatidylinositol 3-kinase and p70S6K protein are involved in differentiation of HL-60 cells induced by calcitriol
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Expression of mutant dynamin causes a redistribution of the cation-independent mannose phosphate receptor: analysis by quantitative immunogold electron microscopy
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Shiga and Shiga-like toxins
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The leucine-based motif DDQxxLI is recognized both for internalization and basolateral sorting of invariant chain in MDCK cells
Eur J Cell Biol, 76 (1), 25-32
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Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
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EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
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Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5
EMBO J, 17 (7), 1941-51
PubMed 9524117 -
Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells
J Cell Sci, 111 ( Pt 6), 825-32
PubMed 9472010 -
Autoantibodies to a novel early endosome antigen 1
Clin Immunol Immunopathol, 86 (1), 81-7
PubMed 9434799 -
Characterization of membrane translocation by anthrax protective antigen
Biochemistry, 37 (45), 15737-46
PubMed 9843379 -
Novel protein toxin-based strategy for development of cytotoxic T lymphocyte vaccines
Arch Immunol Ther Exp (Warsz), 46 (6), 341-6
PubMed 9883312 -
Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells
J Cell Biol, 140 (5), 1039-53
PubMed 9490718 -
Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells
Exp Cell Res, 244 (1), 61-70
PubMed 9770349
Publications 1997
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Microtubules are involved in bafilomycin A1-induced tubulation and Rab5-dependent vacuolation of early endosomes
Eur J Cell Biol, 72 (2), 95-103
PubMed 9157016 -
Role of the disulfide bond in Shiga toxin A-chain for toxin entry into cells
J Biol Chem, 272 (17), 11414-9
PubMed 9111051 -
A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function
Cell, 90 (6), 1149-59
PubMed 9323142 -
Structure-function relationship of the ion channel formed by diphtheria toxin in Vero cell membranes
J Membr Biol, 156 (2), 141-8
PubMed 9075645 -
Membrane translocation of diphtheria toxin fragment A exploits early to late endosome trafficking machinery
Mol Microbiol, 23 (3), 445-57
PubMed 9044279 -
Expression of mRNA for a short form of heparin-binding EGF-like growth factor
Gene, 195 (1), 81-6
PubMed 9300824 -
1,25-Dihydroxyvitamin D3 induced activation and subsequent nuclear translocation of MAPK is upstream regulated by PKC in HL-60 cells
Biochem Biophys Res Commun, 241 (2), 419-26
PubMed 9425286 -
Effect of mutation of cytoplasmic receptor domain and of genistein on transport of acidic fibroblast growth factor into cells
Oncogene, 15 (5), 525-36
PubMed 9247306 -
Role of Rab GTPases in membrane traffic
Int Rev Cytol, 176, 1-85
PubMed 9394917 -
[Self-inhibiting N-glycosidase activity of shigella toxin]
Mol Biol (Mosk), 31 (3), 528-35
PubMed 9297098 -
Self-inhibition of N-glycosidase activity of shiga toxin
Mol. Biol., 31 (3), 441-447 -
Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol
Proc Natl Acad Sci U S A, 94 (8), 3783-8
PubMed 9108055 -
Intracellular transport and processing of protein toxins produced by enteric bacteria
Adv Exp Med Biol, 412, 225-32
PubMed 9192018 -
Performance management in the Swedish police service
41ST ANNUAL EOQ CONGRESS, PROCEEDINGS VOL 2, 43-46 -
Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling
Arch Immunol Ther Exp (Warsz), 45 (5-6), 391-409
PubMed 9437495
Publications 1996
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Comparison of a diffractive bifocal and a monofocal intraocular lens
J Cataract Refract Surg, 22 (4), 446-51
PubMed 8733848 -
Clathrin-dependent and clathrin-independent endocytosis in liver cells
Z Gastroenterol, 34 Suppl 3, 92-4
PubMed 8767476 -
Density shift of endocytic vesicles induced by uptake of colloidal gold particles in rat hepatocytes
Z Gastroenterol, 34 Suppl 3, 79-80
PubMed 8767471 -
Ability of methotrexate to inhibit translocation to the cytosol of dihydrofolate reductase fused to diphtheria toxin
Biochem J, 313 ( Pt 2), 647-53
PubMed 8573105 -
GPI-anchored diphtheria toxin receptor allows membrane translocation of the toxin without detectable ion channel activity
EMBO J, 15 (4), 725-34
PubMed 8631294 -
Effect of calmodulin antagonists on endocytosis and intracellular transport of ricin in polarized MDCK cells
Exp Cell Res, 227 (2), 298-308
PubMed 8831568 -
Thapsigargin-induced transport of cholera toxin to the endoplasmic reticulum
Proc Natl Acad Sci U S A, 93 (22), 12339-43
PubMed 8901582 -
Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells
Mol Biol Cell, 7 (9), 1391-404
PubMed 8885234 -
Endocytosis, intracellular transport, and cytotoxic action of Shiga toxin and ricin
Physiol Rev, 76 (4), 949-66
PubMed 8874490 -
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
PubMed 8798641 -
Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation
J Cell Sci, 109 ( Pt 12), 2905-14
PubMed 9013338 -
Inhibition of the vacuolar H(+)-ATPase with bafilomycin reduces delivery of internalized molecules from mature multivesicular endosomes to lysosomes in HEp-2 cells
Eur J Cell Biol, 69 (4), 343-50
PubMed 8741216 -
Destabilization of plasma membrane structure by prevention of actin polymerization. Microtubule-dependent tubulation of the plasma membrane
J Cell Sci, 109 ( Pt 7), 1655-65
PubMed 8832388 -
[The Anders Jahre medical awarad 1996]
Tidsskr Nor Laegeforen, 116 (23), 2804-6
PubMed 8928170 -
Retrograde transport of acidic fibroblast growth factor as a part of the growth factor signaling
Arch Immunol Ther Exp (Warsz), 44 (4), 201-7
PubMed 9017159 -
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
PubMed 8524304
Publications 1995
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CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168 -
Cell-mediated reduction and incomplete membrane translocation of diphtheria toxin mutants with internal disulfides in the A fragment
J Biol Chem, 270 (35), 20787-93
PubMed 7657662 -
Farnesylation of CaaX-tagged diphtheria toxin A-fragment as a measure of transfer to the cytosol
Biochemistry, 34 (35), 11152-9
PubMed 7669773 -
Role of processing and intracellular transport for optimal toxicity of Shiga toxin and toxin mutants
Exp Cell Res, 218 (1), 39-49
PubMed 7737376 -
Furin-induced cleavage and activation of Shiga toxin
J Biol Chem, 270 (18), 10817-21
PubMed 7738018 -
Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors
Biochem J, 311 ( Pt 1), 317-26
PubMed 7575471 -
Phorbol myristate acetate selectively stimulates apical endocytosis via protein kinase C in polarized MDCK cells
Exp Cell Res, 217 (1), 157-68
PubMed 7867714 -
Involvement of early and late lysosomes in the degradation of mannosylated ligands by rat liver endothelial cells
Exp Cell Res, 216 (2), 290-8
PubMed 7843273 -
Diphtheria toxin endocytosis and membrane translocation are dependent on the intact membrane-anchored receptor (HB-EGF precursor): studies on the cell-associated receptor cleaved by a metalloprotease in phorbol-ester-treated cells
Biochem J, 310 ( Pt 1), 285-9
PubMed 7646457 -
EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif
J Biol Chem, 270 (22), 13503-11
PubMed 7768953 -
Yeast Ypt51p and mammalian Rab5: counterparts with similar function in the early endocytic pathway
J Cell Sci, 108 ( Pt 11), 3509-21
PubMed 8586662 -
Expression of Rab GTPases using recombinant vaccinia viruses
Methods Enzymol, 257, 155-64
PubMed 8583918 -
Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion
Cell, 83 (3), 423-32
PubMed 8521472 -
Induction of toxin sensitivity in insect cells by infection with baculovirus encoding diphtheria toxin receptor
J Biol Chem, 270 (28), 16879-85
PubMed 7622504 -
Delivery to lysosomes in the human carcinoma cell line HEp-2 involves an actin filament-facilitated fusion between mature endosomes and preexisting lysosomes
Eur J Cell Biol, 66 (4), 309-23
PubMed 7544728 -
The GDP/GTP cycle of Rab5 in the regulation of endocytotic membrane traffic
Cold Spring Harb Symp Quant Biol, 60, 211-20
PubMed 8824393 -
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
PubMed 8530506 -
Growth inhibition of rat glioma cells in vitro and in vivo by aspirin
J Neurooncol, 24 (2), 171-80
PubMed 7562004
Publications 1994
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The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis
Neuron, 13 (1), 11-22
PubMed 8043272 -
Selective regulation of apical endocytosis in polarized Madin-Darby canine kidney cells by mastoparan and cAMP
J Biol Chem, 269 (28), 18607-15
PubMed 8034609 -
Diphtheria toxin at low pH depolarizes the membrane, increases the membrane conductance and induces a new type of ion channel in Vero cells
EMBO J, 13 (19), 4433-9
PubMed 7523112 -
Inhibition of membrane translocation of diphtheria toxin A-fragment by internal disulfide bridges
J Biol Chem, 269 (11), 8402-7
PubMed 8132565 -
Entry and uncoating of enveloped viruses
Biochem J, 302 ( Pt 2), 313-20
PubMed 8092981 -
Intermediates in translocation of diphtheria toxin across the plasma membrane
J Biol Chem, 269 (6), 4648-52
PubMed 7508447 -
ENTRY OF SHIGA TOXIN INTO CELLS
INT CONGR SER, 1072, 139-146 -
Retrograde transport from the Golgi complex to the ER of both Shiga toxin and the nontoxic Shiga B-fragment is regulated by butyric acid and cAMP
J Cell Biol, 126 (1), 53-64
PubMed 8027186 -
Endocytosis without clathrin
Trends Cell Biol, 4 (8), 275-7
PubMed 14731589 -
Endocytosis and intracellular sorting of ricin and Shiga toxin
FEBS Lett, 346 (1), 99-102
PubMed 8206167 -
ENTRY OF SHIGA TOXIN INTO CELLS
ZBL BAKT S, 24, 365-374 -
Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast
J Cell Biol, 125 (2), 283-98
PubMed 8163546 -
ROLE OF 3 RAB5-LIKE GTPASES, YPT51P, YPT52P, AND YPT53P, IN THE ENDOCYTIC AND VACUOLAR PROTEIN SORTING PATHWAYS OF YEAST
J. Cell Biol., 125 (2), 283-298 -
A NEW GENE REQUIRED FOR CELLULOSE PRODUCTION AND A GENE ENCODING CELLULOLYTIC ACTIVITY IN ACETOBACTER-XYLINUM ARE COLOCALIZED WITH THE BCS OPERON (VOL 176, PG 665, 1994)
J. Bacteriol., 176 (11), 3443 -
A new gene required for cellulose production and a gene encoding cellulolytic activity in Acetobacter xylinum are colocalized with the bcs operon
J Bacteriol, 176 (3), 665-72
PubMed 8300521 -
Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis
EMBO J, 13 (6), 1287-96
PubMed 8137813 -
Distinct structural elements of rab5 define its functional specificity
EMBO J, 13 (3), 575-83
PubMed 8313902 -
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
PubMed 7511061
Publications 1993
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Membrane translocation of diphtheria toxin A-fragment: role of carboxy-terminal region
Biochemistry, 32 (1), 83-90
PubMed 8418864 -
A chimeric toxin to study the role of the 21 kDa GTP binding protein rho in the control of actin microfilament assembly
EMBO J, 12 (3), 921-31
PubMed 8458345 -
PRELYSOSOMAL DEGRADATION IN RAT-LIVER ENDOTHELIAL-CELLS
CELLS OF THE HEPATIC SINUSOID, VOL 4, 426-430 -
Receptor-mediated endocytosis of ricin in rat liver endothelial cells. An immunocytochemical study
Eur J Cell Biol, 60 (1), 154-62
PubMed 8462592 -
Subcloning and characterization of the binding domain of fragment B of diphtheria toxin
Biochem J, 294 ( Pt 3), 663-6
PubMed 8379922 -
Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification
J Cell Biol, 121 (1), 61-72
PubMed 8458873 -
Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors
J Cell Biol, 123 (1), 89-97
PubMed 8408209 -
Endocytosis of desmosomal plaques depends on intact actin filaments and leads to a nondegradative compartment
Eur J Cell Biol, 62 (2), 362-71
PubMed 7925492 -
New cloning opportunities with the use of noncomplementary SfiI adaptors
Biotechniques, 15 (6), 980-2
PubMed 8292350 -
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
PubMed 8411117 -
Entry of protein toxins in polarized epithelial cells
Cancer Res, 53 (8), 1755-60
PubMed 8467493 -
EFFECT OF MONENSIN ON RICIN AND FLUID PHASE TRANSPORT IN FILTER-GROWN MDCK-CELLS
ZBL BAKT S, 23, 361-362 -
Rapid cellular removal of a membrane-inserted foreign polypeptide
Biochem J, 291 ( Pt 2), 473-7
PubMed 8484728 -
INTERNALIZATION OF DIPHTHERIA AND RELATED TOXINS
ZBL BAKT S, 23, 341-348 -
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
PubMed 8392658 -
Amplification of c-erbB-2, int-2 and c-myc genes in node-negative breast carcinomas. Relationship to prognosis
Acta Oncol, 32 (3), 289-94
PubMed 8100712 -
Entry of Shiga toxin into cells
Zentralbl Bakteriol, 278 (2-3), 296-305
PubMed 8347933 -
Endocytosis and intracellular transport of protein toxins
Biochem Soc Trans, 21 ( Pt 3) (3), 707-11
PubMed 8224494 -
Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins
J Biol Chem, 268 (24), 18143-50
PubMed 8349690 -
Multivesicular bodies in HEp-2 cells are maturing endosomes
Eur J Cell Biol, 61 (2), 208-24
PubMed 8223712 -
Are caveolae involved in clathrin-independent endocytosis?
Trends Cell Biol, 3 (8), 249-51
PubMed 14731741 -
Rab GTPases in vesicular transport
Curr Opin Cell Biol, 5 (4), 613-20
PubMed 8257602
Publications 1992
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Replacement of negative by positive charges in the presumed membrane-inserted part of diphtheria toxin B fragment. Effect on membrane translocation and on formation of cation channels
J Biol Chem, 267 (17), 12284-90
PubMed 1376320 -
Internalization efficiency of the transferrin receptor
Exp Cell Res, 199 (1), 19-28
PubMed 1735458 -
Comparative studies on internalization of gold labelled mistletoe lectin I (MLI), its subunits, and of an immunotoxin into mouse L 1210V leukemia cells
Acta Histochem, 92 (1), 46-53
PubMed 1580141 -
Membrane translocation of diphtheria toxin carrying passenger protein domains
Infect Immun, 60 (8), 3296-302
PubMed 1639497 -
Entry of ADP-ribosylating toxins into cells
Curr Top Microbiol Immunol, 175, 1-26
PubMed 1378368 -
Shiga toxin: biochemistry, genetics, mode of action, and role in pathogenesis
Curr Top Microbiol Immunol, 180, 65-94
PubMed 1324134 -
PROTEIN TRANSLOCATION FROM THE EXTERIOR TO THE CYTOSOL - DIPHTHERIA-TOXIN AS A MODEL SYSTEM
FEMS SYMP, 61, 221-225 -
Genetically engineered toxins in perspective
Targeted Diagn Ther, 7, 465-77
PubMed 1633307 -



