
| Eivind Hovig | |
| Position: | Group leader |
| Phone: | +47 2278 1778 |
| Email: | |
Publications in press
Cyclodextrin-Containing Polymer Delivery System for Light-Directed siRNA Gene Silencing
Oligonucleotides (in press)
PubMed 20645877
Publications 2010
Light-induced gene expression using messenger RNA molecules
Oligonucleotides, 20 (1), 1-6
PubMed 20038251
Publications 2009
Non-parametric estimation of reference intervals in small non-Gaussian sample sets
Accredit. Qual. Assur., 14 (4), 185-192
Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
Methods Mol Biol, 524, 273-85
PubMed 19377952
Upregulation of stem cell genes in multidrug resistant K562 leukemia cells
Leuk Res, 33 (10), 1379-85
PubMed 19394083
The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts
Nucleic Acids Res, 37 (17), 5749-56
PubMed 19617376
Large-scale inference of the point mutational spectrum in human segmental duplications
BMC Genomics, 10, 43
PubMed 19161616
Methods for quantitation of gene expression
Front Biosci, 14, 552-69
PubMed 19273085
The mathematics of tanning
BMC Syst Biol, 3, 60
PubMed 19505344
Segmentation of DNA sequences into twostate regions and melting fork regions
J. Phys.-Condes. Matter, 21 (3), 034109
Publications 2008
Evaluation of various polyethylenimine formulations for light-controlled gene silencing using small interfering RNA molecules
Oligonucleotides, 18 (2), 123-32
PubMed 18637730
Activation of NF-kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes
Int J Cancer, 123 (6), 1301-10
PubMed 18548584
The majority of viral-cellular fusion transcripts in cervical carcinomas cotranscribe cellular sequences of known or predicted genes
Cancer Res, 68 (7), 2514-22
PubMed 18381461
GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
Genome Biol, 9 (5), R86
PubMed 18500990
Cell sampling and global nucleic acid amplification
SEB Exp Biol Ser, 61, 17-36
PubMed 18709735
Validation of oligoarrays for quantitative exploration of the transcriptome
BMC Genomics, 9, 258
PubMed 18513391
Publications 2007
Connectivity can be used to identify key genes in DNA microarray data: a study based on gene expression in nasal polyps before and after treatment with glucocorticoids
Acta Otolaryngol, 127 (10), 1074-9
PubMed 17851899
Photochemically induced gene silencing using small interfering RNA molecules in combination with lipid carriers
Oligonucleotides, 17 (2), 166-73
PubMed 17638521
Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
J Mol Biol, 365 (1), 90-108
PubMed 17054988
Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
Methods Mol Biol, 360, 335-48
PubMed 17172738
Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
BMC Genomics, 8, 273
PubMed 17692132
Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates
BMC Genomics, 8, 153
PubMed 17555589
The human genomic melting map
PLoS Comput Biol, 3 (5), e93
PubMed 17511513
Genetic epidemiology of BRCA mutations--family history detects less than 50% of the mutation carriers
Eur J Cancer, 43 (11), 1713-7
PubMed 17574839
Publications 2006
Sampling effects on gene expression data from a human tumour xenograft
Scand. J. Lab. Anim. Sci., 33 (1), 17-30
Photochemically induced gene silencing using PNA-peptide conjugates
Oligonucleotides, 16 (2), 145-57
PubMed 16764538
A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
Nat Biotechnol, 24 (7), 832-40
PubMed 16823376
Options available for profiling small samples: a review of sample amplification technology when combined with microarray profiling
Nucleic Acids Res, 34 (3), 996-1014
PubMed 16473852
Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
FEBS Lett, 580 (24), 5739-46
PubMed 17007842
MUTYH Mutations Do Not Cause HNPCC or Late Onset Familial Colorectal Cancer
Hered Cancer Clin Pract, 4 (2), 90-3
PubMed 20223013
Publications 2005
Parallel nanoliter detection of cancer markers using polymer microchips
Lab Chip, 5 (4), 416-20
PubMed 15791339
Gene-expression profiling in breast cancer
Lancet, 365 (9460), 634-5
PubMed 15721457
Response of malignant B lymphocytes to ionizing radiation: gene expression and genotype
Int J Cancer, 115 (6), 935-42
PubMed 15723354
Limitations of mRNA amplification from small-size cell samples
BMC Genomics, 6, 147
PubMed 16253144
Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles
Nucleic Acids Res, 33 (Web Server issue), W573-6
PubMed 15980539
Publications 2004
BRCA1 mutations in ovarian cancer and borderline tumours in Norway: a nested case-control study
Br J Cancer, 91 (10), 1829-34
PubMed 15477862
Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
Proteomics, 4 (9), 2572-82
PubMed 15352232
Double-sided silicon strip detectors: new applications within genomics and proteomics
Nucl. Instrum. Methods Phys. Res. Sect. A-Accel. Spectrom. Dect. Assoc. Equip., 527 (1-2), 68-72
The detection of hamster connexins: a comparison of expression profiles with wild-type mouse and the cancer-prone Min mouse
Cell Commun Adhes, 11 (5-6), 155-71
PubMed 16194882
Determination of hereditary mutations in the BRCA1 gene using archived serum samples and capillary electrophoresis
Anal Chem, 76 (15), 4406-9
PubMed 15283579
Real-time nucleic acid sequence-based amplification in nanoliter volumes
Anal Chem, 76 (1), 9-14
PubMed 14697026
FigSearch: a figure legend indexing and classification system
Bioinformatics, 20 (16), 2880-2
PubMed 15145804
FigSearch: Using maximum entropy classifier to categorize biological figures
2004 IEEE COMPUTATIONAL SYSTEMS BIOINFORMATICS CONFERENCE, PROCEEDINGS, 476-477
Profound influence of microarray scanner characteristics on gene expression ratios: analysis and procedure for correction
BMC Genomics, 5 (1), 10
PubMed 15018648
Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma
J Mol Diagn, 6 (4), 297-307
PubMed 15507668
Publications 2003
Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest
Br J Cancer, 88 (12), 1995-2001
PubMed 12799648
S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells
Clin Exp Metastasis, 20 (8), 701-11
PubMed 14713104
Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
BMC Genomics, 4 (1), 11
PubMed 12659661
Speed-up of DNA melting algorithm with complete nearest neighbor properties
Biopolymers, 70 (3), 364-76
PubMed 14579309
Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data
BMC Bioinformatics, 4, 60
PubMed 14651757
MGraph: graphical models for microarray data analysis
Bioinformatics, 19 (17), 2210-1
PubMed 14630649
Publications 2002
The semantic web and biology
Drug Discov Today, 7 (19), 992
PubMed 12546914
Associations between gene expressions in breast cancer and patient survival
Hum Genet, 111 (4-5), 411-20
PubMed 12384785
Analysis of repeatability in spotted cDNA microarrays
Nucleic Acids Res, 30 (14), 3235-44
PubMed 12136105
Differential display analysis of breast carcinoma cells enriched by immunomagnetic target cell selection: gene expression profiles in bone marrow target cells
Int J Cancer, 97 (1), 28-33
PubMed 11774240
MArray: analysing single, replicated or reversed microarray experiments
Bioinformatics, 18 (8), 1139-40
PubMed 12176840
Publications 2001
Detection of mutations by denaturing gradient gel electrophoresis
Curr Protoc Hum Genet, Chapter 7, Unit 7.5
PubMed 18428306
Optimization of hammerhead ribozymes for the cleavage of S100A4 (CAPL) mRNA
Antisense Nucleic Acid Drug Dev, 11 (2), 67-75
PubMed 11334142
[Gene therapy in cancer]
Tidsskr Nor Laegeforen, 121 (4), 482-8
PubMed 11255868
CA 125: the end of the beginning
Tumour Biol, 22 (6), 345-7
PubMed 11786728
A literature network of human genes for high-throughput analysis of gene expression
Nat Genet, 28 (1), 21-8
PubMed 11326270
[New knowledge derived from measurement of gene expression with the DNA microarray method]
Tidsskr Nor Laegeforen, 121 (10), 1229-32
PubMed 11402750
The BRCA1 syndrome and other inherited breast or breast-ovarian cancers in a Norwegian prospective series
Eur J Cancer, 37 (8), 1027-32
PubMed 11334729
Genetic epidemiology of BRCA1 mutations in Norway
Eur J Cancer, 37 (18), 2428-34
PubMed 11720839
Detection of mutations by single-strand conformation polymorphism (SSCP) analysis and SSCP-hybrid methods
Curr Protoc Hum Genet, Chapter 7, Unit 7.4
PubMed 18428305
Publications 1999
S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme
Cancer Res, 59 (18), 4702-8
PubMed 10493528
BRCA1 1675delA and 1135insA account for one third of Norwegian familial breast-ovarian cancer and are associated with later disease onset than less frequent mutations
Dis Markers, 15 (1-3), 79-84
PubMed 10595257
Penetrances of BRCA1 1675delA and 1135insA with respect to breast cancer and ovarian cancer
Am J Hum Genet, 65 (3), 671-9
PubMed 10441573
Three per cent of Norwegian ovarian cancers are caused by BRCA1 1675delA or 1135insA
Eur J Cancer, 35 (5), 779-81
PubMed 10505039
Expression of a novel factor in human breast cancer cells with metastatic potential
Cancer Res, 59 (18), 4675-80
PubMed 10493524
Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells
Int J Cancer, 80 (1), 119-25
PubMed 9935241
Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53
Hum Genet, 104 (1), 15-22
PubMed 10071187
Publications 1998
Interleukin-1 alpha and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL
Anticancer Res, 18 (5A), 3299-303
PubMed 9858899
Intracellular metabolism of a 2'-O-methyl-stabilized ribozyme after uptake by DOTAP transfection or asfree ribozyme. A study by capillary electrophoresis
Nucleic Acids Res, 26 (18), 4241-8
PubMed 9722645
Publications 1997
Ectopic expression of target genes may represent an inherent limitation of RT-PCR assays used for micrometastasis detection: studies on the epithelial glycoprotein gene EGP-2
Int J Cancer, 72 (1), 191-6
PubMed 9212242
A BRCA1 founder mutation, identified with haplotype analysis, allowing genotype/phenotype determination and predictive testing
Eur J Cancer, 33 (14), 2390-2
PubMed 9616287
Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects
Nucleic Acids Res, 25 (1), 151-7
PubMed 9016527
Differential expression patterns of S100A2, S100A4 and S100A6 during progression of human malignant melanoma
Int J Cancer, 74 (4), 464-9
PubMed 9291441
Publications 1996
Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation
Nucleic Acids Res, 24 (1), 141-6
PubMed 8594564
[Prostate-specific membrane antigen]
Tidsskr Nor Laegeforen, 116 (3), 411-2
PubMed 8638273
Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas
Br J Cancer, 73 (8), 909-16
PubMed 8611425
Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozyme
Cancer Res, 56 (23), 5490-8
PubMed 8968106
CDKN2A (p16INK4A) somatic and germline mutations
Hum Mutat, 7 (4), 294-303
PubMed 8723678
Publications 1995
Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
Lab Invest, 72 (4), 411-8
PubMed 7723279
Somatic spectrum of cancer-associated single basepair substitutions in the TP53 gene is determined mainly by endogenous mechanisms of mutation and by selection
Hum Mutat, 5 (1), 48-57
PubMed 7728149
Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1
Br J Cancer, 72 (2), 393-8
PubMed 7640224
REVERSAL OF THE IN-VIVO METASTATIC PHENOTYPE OF HUMAN OSTEOSARCOMA CELLS BY AN ANTI-CAPL (MTS-1) RIBOZYME (VOL 55, PG 77, 1995)
Cancer Res., 55 (11), 2484
Publications 1994
Database of p53 gene somatic mutations in human tumors and cell lines
Nucleic Acids Res, 22 (17), 3551-5
PubMed 7937055
Publications 1993
p53 abnormalities in different subtypes of human sarcomas
Cancer Res, 53 (3), 468-71
PubMed 8425179
Genome scanning of human breast carcinomas using micro- and minisatellite core probes
Genomics, 17 (1), 66-75
PubMed 8104870
Publications 1992
Screening for germ line TP53 mutations in breast cancer patients
Cancer Res, 52 (11), 3234-6
PubMed 1591732
A TP53 mutation detected in cells established from an osteosarcoma, but not in the retinoblastoma of a patient with bilateral retinoblastoma and multiple primary osteosarcomas
Cancer Genet Cytogenet, 64 (2), 178-82
PubMed 1336709
No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung
Genes Chromosomes Cancer, 5 (2), 97-103
PubMed 1381957
Detection of DNA variation in cancer
Pharmacogenetics, 2 (6), 317-28
PubMed 1306133
Screening for mutations in human HPRT cDNA using the polymerase chain reaction (PCR) in combination with constant denaturant gel electrophoresis (CDGE)
Mutat Res, 269 (1), 41-53
PubMed 1381470
Publications 1991
T-cell receptor tau delta +/CD3+4-8-T- cell acute lymphoblastic leukemias: a distinct subgroup of leukemias in children. A report of five cases
Blood, 77 (9), 2023-30
PubMed 1826854
Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations
Proc Natl Acad Sci U S A, 88 (19), 8405-9
PubMed 1924299
Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
Mutat Res, 263 (1), 61
PubMed 2034242
Chromosome 13 alterations in osteosarcoma cell lines derived from a patient with previous retinoblastoma
Cancer Genet Cytogenet, 57 (1), 31-40
PubMed 1684533
Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
Mutat Res, 262 (1), 63-71
PubMed 1702518
EFFECTS OF PDT ON DNA AND CHROMOSOMES
PHOTOBIOLOGY - THE SCIENCE AND ITS APPLICATIONS , 821-829
Publications 1990
SCREENING FOR BASE MUTATIONS IN THE PAH AND HPRT LOCI USING THE POLYMERASE CHAIN-REACTION (PCR) IN COMBINATION WITH DENATURING GRADIENT GEL-ELECTROPHORESIS (DGGE)
Prog.Clin.Biol.Res. , 340, 389-398
Screening for base mutations in the PAH and HPRT loci using the polymerase chain reaction (PCR) in combination with denaturing gradient gel electrophoresis (DGGE)
Prog Clin Biol Res, 340A, 389-98
PubMed 2388921
Publications 1989
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882
Publications 1988
Detection of base mutations in genomic DNA using denaturing gradient gel electrophoresis (DGGE) followed by transfer and hybridization with gene-specific probes
Mutat Res, 202 (1), 77-83
PubMed 2903443
Publications 1987
Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
Cancer Genet Cytogenet, 24 (2), 327-34
PubMed 2878716




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