Publications in press

Morrow DI, McCarron PA, Woolfson AD, Juzenas P, Juzeniene A, Iani V, Moan J, Donnelly RF
Novel patch-based systems for the localised delivery of ALA-esters
J Photochem Photobiol B (in press)
PubMed 20634088

Publications 2010

Morrow DI, McCarron PA, Woolfson AD, Juzenas P, Juzeniene A, Iani V, Moan J, Donnelly RF (2010)
Hexyl aminolaevulinate is a more effective topical photosensitiser precursor than methyl aminolaevulinate and 5-aminolaevulinic acids when applied in equimolar doses
J Pharm Sci, 99 (8), 3486-98
PubMed 20222026

Morrow DI, McCarron PA, Woolfson AD, Juzenas P, Juzeniene A, Iani V, Moan J, Donnelly RF (2010)
Influence of penetration enhancers on topical delivery of 5-aminolevulinic acid from bioadhesive patches
J Pharm Pharmacol, 62 (6), 685-95
PubMed 20636855

Publications 2009

Donnelly RF, McCarron PA, Al-Kassas R, Juzeniene A, Juzenas P, Iani V, Woolfson AD, Moan J (2009)
Influence of formulation factors on PpIX production and photodynamic action of novel ALA-loaded microparticles
Biopharm Drug Dispos, 30 (2), 55-70
PubMed 19226650

Donnelly RF, Morrow DI, McCarron PA, David Woolfson A, Morrissey A, Juzenas P, Juzeniene A, Iani V, McCarthy HO, Moan J (2009)
Microneedle arrays permit enhanced intradermal delivery of a preformed photosensitizer
Photochem Photobiol, 85 (1), 195-204
PubMed 18764907

Juzenas P, Juzeniene A, Iani V, Moan J (2009)
Depth profile of protoporphyrin IX fluorescence in an amelanotic mouse melanoma model
Photochem Photobiol, 85 (3), 760-4
PubMed 19140894

Juzeniene A, Thu Tam TT, Iani V, Moan J (2009)
5-Methyltetrahydrofolate can be photodegraded by endogenous photosensitizers
Free Radic Biol Med, 47 (8), 1199-204
PubMed 19647791

Mikolajewska P, Iani V, Juzeniene A, Moan J (2009)
Topical aminolaevulinic acid- and aminolaevulinic acid methyl ester-based photodynamic therapy with red and violet light: influence of wavelength on pain and erythema
Br J Dermatol, 161 (5), 1173-9
PubMed 19785604

Pudroma X, Moan J, Ma LW, Iani V, Juzeniene A (2009)
A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin
Exp Dermatol, 18 (11), 985-7
PubMed 19469901

Tam TT, Juzeniene A, Steindal AH, Iani V, Moan J (2009)
Photodegradation of 5-methyltetrahydrofolate in the presence of Uroporphyrin
J Photochem Photobiol B, 94 (3), 201-4
PubMed 19138530

Publications 2008

Donnelly RF, Morrow DI, McCarron PA, Woolfson AD, Morrissey A, Juzenas P, Juzeniene A, Iani V, McCarthy HO, Moan J (2008)
Microneedle-mediated intradermal delivery of 5-aminolevulinic acid: potential for enhanced topical photodynamic therapy
J Control Release, 129 (3), 154-62
PubMed 18556084

Publications 2007

Juzeniene A, Juzenas P, Iani V, Moan J (2007)
Topical applications of iron chelators in photosensitization
Photochem Photobiol Sci, 6 (12), 1268-74
PubMed 18046481

Kaliszewski M, Kwasny M, Juzeniene A, Juzenas P, Graczyk A, Ma LW, Iani V, Mikolajewska P, Moan J (2007)
Biological activity of 5-aminolevulinic acid and its methyl ester after storage under different conditions
J Photochem Photobiol B, 87 (2), 67-72
PubMed 17350278

Ma LW, Nielsen KP, Iani V, Moan J (2007)
A new method for photodynamic therapy of melanotic melanoma -- effects of depigmentation with violet light photodynamic therapy
J Environ Pathol Toxicol Oncol, 26 (3), 165-72
PubMed 18197832

Publications 2006

Bronshteint I, Aulova S, Juzeniene A, Iani V, Ma LW, Smith KM, Malik Z, Moan J, Ehrenberg B (2006)
In vitro and in vivo photosensitization by protoporphyrins possessing different lipophilicities and vertical localization in the membrane
Photochem Photobiol, 82 (5), 1319-25
PubMed 16740058

Bugaj A, Juzeniene A, Juzenas P, Iani V, Ma LW, Moan J (2006)
The effect of skin permeation enhancers on the formation of porphyrins in mouse skin during topical application of the methyl ester of 5-aminolevulinic acid
J Photochem Photobiol B, 83 (2), 94-7
PubMed 16442808

Donnelly RF, Ma LW, Juzenas P, Iani V, McCarron PA, Woolfson AD, Moan J (2006)
Topical bioadhesive patch systems enhance selectivity of protoporphyrin IX accumulation
Photochem Photobiol, 82 (3), 670-5
PubMed 16475870

Donnelly RF, McCarron PA, Ma LW, Juzenas P, Iani V, Woolfson AD, Zawislak AA, Moan J (2006)
Facilitated delivery of ALA to inaccessible regions via bioadhesive patch systems
J. Environ. Pathol. Toxicol. Oncol., 25 (1-2), 389-402

Juzenas P, Juzeniene A, Iani V, Moan J (2006)
The influence of light and darkness on cutaneous fluorescence in mice
Luminescence, 21 (3), 159-63
PubMed 16502394

Juzeniene A, Juzenas P, Ma LW, Iani V, Moan J (2006)
Topical application of 5-aminolaevulinic acid, methyl 5-aminolaevulinate and hexyl 5-aminolaevulinate on normal human skin
Br J Dermatol, 155 (4), 791-9
PubMed 16965430

Ma L, Steindal AE, Juzeniene A, Iani V, Moan J (2006)
The effect of folic acid on porphyrin synthesis in tumors and normal skin of mice treated with 5-aminolevulinic acid or methyl 5-aminolevulinate
Photochem Photobiol Sci, 5 (8), 755-9
PubMed 16886091

Veberg A, Sorheim O, Moan J, Iani V, Juzenas P, Nilsen AN, Wold JP (2006)
Measurement of lipid oxidation and porphyrins in high oxygen modified atmosphere and vacuum-packed minced turkey and pork meat by fluorescence spectra and images
Meat Sci., 73 (3), 511-520

Publications 2005

Bender J, Ericson MB, Merclin N, Iani V, Rosén A, Engström S, Moan J (2005)
Lipid cubic phases for improved topical drug delivery in photodynamic therapy
J Control Release, 106 (3), 350-60
PubMed 15967535

Kristiansson S, Juzeniene A, Juzenas P, Iani V, Löfgren L, Moan J (2005)
Kinetics of protoporphyrin IX formation in rat oral mucosa and skin after application of 5-aminolevulinic acid and its methylester
Photochem Photobiol, 81 (2), 394-7
PubMed 15535733

Moan J, Ma L, Iani V, Juzeniene A (2005)
Influence of light exposure on the kinetics of protoporphyrin IX formation in normal skin of hairless mice after application of 5-aminolevulinic acid methyl ester
J Invest Dermatol, 125 (5), 1039-44
PubMed 16297207

Wold JP, Veberg A, Nilsen A, Iani V, Juzenas P, Moan J (2005)
The role of naturally occurring chlorophyll and porphyrins in light-induced oxidation of dairy products. A study based on fluorescence spectroscopy and sensory analysis
Int. Dairy J., 15 (4), 343-353

Publications 2004

Juzeniene A, Juzenas P, Ma LW, Iani V, Moan J (2004)
Effectiveness of different light sources for 5-aminolevulinic acid photodynamic therapy
Lasers Med Sci, 19 (3), 139-49
PubMed 15503248

Lassalle HP, Bezdetnaya L, Iani V, Juzeniene A, Guillemin F, Moan J (2004)
Photodegradation and phototransformation of 5,10,15,20-tetrakis(m-hydroxyphenyl)bacteriochlorin (m-THPBC) in solution
Photochem Photobiol Sci, 3 (11-12), 999-1005
PubMed 15570386

Publications 2003

Moan J, Ma LW, Juzeniene A, Iani V, Juzenas P, Apricena F, Peng Q (2003)
Pharmacology of protoporphyrin IX in nude mice after application of ALA and ALA esters
Int J Cancer, 103 (1), 132-5
PubMed 12455066

Publications 2002

Juzenas P, Juzeniene A, Kaalhus O, Iani V, Moan J (2002)
Noninvasive fluorescence excitation spectroscopy during application of 5-aminolevulinic acid in vivo
Photochem Photobiol Sci, 1 (10), 745-8
PubMed 12656473

Juzenas P, Juzeniene A, Stakland S, Iani V, Moan J (2002)
Photosensitizing effect of protoporphyrin IX in pigmented melanoma of mice
Biochem Biophys Res Commun, 297 (3), 468-72
PubMed 12270116

Juzeniene A, Juzenas P, Iani V, Moan J (2002)
Topical application of 5-aminolevulinic acid and its methylester, hexylester and octylester derivatives: considerations for dosimetry in mouse skin model
Photochem Photobiol, 76 (3), 329-34
PubMed 12403455

Juzeniene A, Juzenas P, Kaalhus O, Iani V, Moan J (2002)
Temperature effect on accumulation of protoporphyrin IX after topical application of 5-aminolevulinic acid and its methylester and hexylester derivatives in normal mouse skin
Photochem Photobiol, 76 (4), 452-6
PubMed 12405155

Juzeniene A, Ma LW, Juzenas P, Iani V, Lange N, Moan J (2002)
Production of protoporphyrin IX from 5-aminolevulinic acid and two of its esters in cells in vitro and tissues in vivo
Cell Mol Biol (Noisy-le-grand), 48 (8), 911-6
PubMed 12699250

Uzdensky AB, Iani V, Ma LW, Moan J (2002)
Photobleaching of hypericin bound to human serum albumin, cultured adenocarcinoma cells and nude mice skin
Photochem Photobiol, 76 (3), 320-8
PubMed 12403454

van den Akker JT, Iani V, Star WM, Sterenborg HJ, Moan J (2002)
Systemic component of protoporphyrin IX production in nude mouse skin upon topical application of aminolevulinic acid depends on the application conditions
Photochem Photobiol, 75 (2), 172-7
PubMed 11885562

Publications 2001

Juzenas P, Iani V, Bagdonas S, Rotomskis R, Moan J (2001)
Fluorescence spectroscopy of normal mouse skin exposed to 5-aminolaevulinic acid and red light
J Photochem Photobiol B, 61 (1-2), 78-86
PubMed 11485851

Moan J, Ma LW, Iani V (2001)
On the pharmacokinetics of topically applied 5-aminolevulinic acid and two of its esters
Int J Cancer, 92 (1), 139-43
PubMed 11279617

Moan J, Ma LW, Iani V, Juzenas P (2001)
Mechanisms and procedures in PDT
SKIN AND ENVIRONMENT - PERCEPTION AND PROTECTION, VOLS 1 AND 2, 641-647

Moan J, Van den Akker JTHM, Juzenas P, Ma LW, Angell-Petersen E, Gadmar OB, Iani V (2001)
On the basis for tumor selectivity in the 5-aminolevulinic acid-induced synthesis of protoporphyrin IX
J. Porphyr. Phthalocyanines, 5 (2), 170-176

Uzdensky AB, Ma LW, Iani V, Hjortland GO, Steen HB, Moan J (2001)
Intracellular localisation of hypericin in human glioblastoma and carcinoma cell lines
Lasers Med Sci, 16 (4), 276-83
PubMed 11702633

von Beckerath M, Juzenas P, Ma LW, Iani V, Löfgren L, Moan J (2001)
The influence of UV exposure on 5-aminolevulinic acid-induced protoporphyrin IX production in skin
Photochem Photobiol, 74 (6), 825-8
PubMed 11783939

Publications 2000

Bagdonas S, Ma LW, Iani V, Rotomskis R, Juzenas P, Moan J (2000)
Phototransformations of 5-aminolevulinic acid-induced protoporphyrin IX in vitro: a spectroscopic study
Photochem Photobiol, 72 (2), 186-92
PubMed 10946571

van den Akker JT, Iani V, Star WM, Sterenborg HJ, Moan J (2000)
Topical application of 5-aminolevulinic acid hexyl ester and 5-aminolevulinic acid to normal nude mouse skin: differences in protoporphyrin IX fluorescence kinetics and the role of the stratum corneum
Photochem Photobiol, 72 (5), 681-9
PubMed 11107855

Publications 1999

Juzenas P, Sorensen R, Iani V, Moan J (1999)
Clearance of protoporphyrin IX from mouse skin after topical application of 5-aminolevulinic acid and its methyl ester
P SOC PHOTO-OPT INSTRUM ENG, 3563, 161-166

Juzenas P, Sørensen R, Iani V, Moan J (1999)
Uptake of topically applied 5-aminolevulinic acid and production of protoporphyrin IX in normal mouse skin: dependence on skin temperature
Photochem Photobiol, 69 (4), 478-81
PubMed 10212580

Moan J, Berg K, Gadmar OB, Iani V, Ma L, Juzenas P (1999)
The temperature dependence of protoporphyrin IX production in cells and tissues
Photochem Photobiol, 70 (4), 669-73
PubMed 10546563

Sorensen R, Juzenas P, Iani V, Moan J (1999)
Formation of protoporphyrin IX in mouse skin after topical application of 5-aminolevulinic acid and its methyl ester.
P SOC PHOTO-OPT INSTRUM ENG, 3563, 77-81

Publications 1998

Ma L, Moan J, Peng Q, Iani V (1998)
Production of protoporphyrin IX induced by 5-aminolevulinic acid in transplanted human colon adenocarcinoma of nude mice can be increased by ultrasound
Int J Cancer, 78 (4), 464-9
PubMed 9797135

Moan J, Iani V, Ma LW (1998)
In vivo fluorescence of phthalocyanines during light exposure
J Photochem Photobiol B, 42 (2), 100-3
PubMed 9540216

Moan J, Peng Q, Sorensen R, Iani V, Nesland JM (1998)
The biophysical foundations of photodynamic therapy
Endoscopy, 30 (4), 387-91
PubMed 9689514

Sørensen R, Iani V, Moan J (1998)
Kinetics of photobleaching of protoporphyrin IX in the skin of nude mice exposed to different fluence rates of red light
Photochem Photobiol, 68 (6), 835-40
PubMed 9867033

Publications 1996

Iani V, Moan J, Ma LW (1996)
Measurements of light penetration into human tissues in vivo
P SOC PHOTO-OPT INSTRUM ENG, 2625, 378-383

Ma LW, Berg K, Danielsen HE, Iani V, Moan J (1996)
Enhancement of the efficiency of photodynamic therapy by combination with the microtubule inhibitor vincristine
P SOC PHOTO-OPT INSTRUM ENG, 2625, 170-178

Ma LW, Berg K, Danielsen HE, Kaalhus O, Iani V, Moan J (1996)
Enhanced antitumour effect of photodynamic therapy by microtubule inhibitors
Cancer Lett, 109 (1-2), 129-39
PubMed 9020912

Ma LW, Moan J, Grahn MF, Iani V (1996)
A comparison of meso-tetrahydroxyphenyl-chlorin and meso-tetrahydroxyphenyl-bacteriochlorin with respect to photobleaching and PCT efficiency in vivo
P SOC PHOTO-OPT INSTRUM ENG, 2924, 219-224

Moan J, Iani V, Ma LW (1996)
Choice of the proper wavelength for photochemotherapy
P SOC PHOTO-OPT INSTRUM ENG, 2625, 544-549

Moan J, Iani V, Ma LW, Peng Q (1996)
Photodegradation of sensitizers in mouse skin during PCT
P SOC PHOTO-OPT INSTRUM ENG, 2625, 187-193

Moan J, Peng QA, Iani V, Ma LW, Horobin RW, Berg K, Kongshaug M, Nesland JM (1996)
Biodistribution, pharmacokinetic and in vivo fluorescence spectroscopic studies of photosensitizers
P SOC PHOTO-OPT INSTRUM ENG, 2625, 234-250

Peng Q, Moan J, Iani V, Nesland JM (1996)
Effect of desferrioxamine on production of ALA-induced protoporphyrin M in normal mouse skin
P SOC PHOTO-OPT INSTRUM ENG, 2625, 51-57

Peng Q, Moan J, Warloe T, Iani V, Steen HB, Bjørseth A, Nesland JM (1996)
Build-up of esterified aminolevulinic-acid-derivative-induced porphyrin fluorescence in normal mouse skin
J Photochem Photobiol B, 34 (1), 95-6
PubMed 8765664

Publications 1995

Ma LW, Moan J, Steen HB, Iani V (1995)
Anti-tumour activity of photodynamic therapy in combination with mitomycin C in nude mice with human colon adenocarcinoma
Br J Cancer, 71 (5), 950-6
PubMed 7734319

MA LW, MOAN J, STEEN HB, IANI V (1995)
ANTITUMOR-ACTIVITY OF PHOTODYNAMIC THERAPY IN COMBINATION WITH MITOMYCIN-C IN NUDE-MICE WITH HUMAN COLON ADENOCARCINOMA
Br. J. Cancer, 71 (5), 950-956

Publications 1993

Ma L, Iani V, Moan J (1993)
Combination therapy: photochemotherapy; electric current; and ionizing radiation. Different combinations studied in a WiDr human colon adenocarcinoma cell line
J Photochem Photobiol B, 21 (2-3), 149-54
PubMed 8301411

RIMINGTON C, RONNESTAD A, IANI V, MOAN J, LAWSON AM (1993)
REACTION OF ISOHEMATOPORPHYRIN WITH 1-BROMOALKANES
Int. J. Biochem., 25 (3), 445-447