Kirsten Skarstad

Publications by Kirsten Skarstad

67 publications found

Publications in press

1. Boeneman K, Fossum S, Yang Y, Fingland N, Skarstad K, Crooke E
   Escherichia coli DnaA forms helical structures along the longitudinal cell axis distinct from MreB filaments
   Mol Microbiol (in press)
   PubMed 19400775

Publications 2009

1. Flåtten I, Morigen, Skarstad K (2009)
   DnaA protein interacts with RNA polymerase and partially protects it from the effect of rifampicin
   Mol Microbiol, 71 (4), 1018-30
   PubMed 19170875
2. Morigen, Odsbu I, Skarstad K (2009)
   Growth rate dependent numbers of SeqA structures organize the multiple replication forks in rapidly growing Escherichia coli
   Genes Cells, 14 (5), 643-57
   PubMed 19371375
3. Odsbu I, Morigen, Skarstad K (2009)
   A reduction in ribonucleotide reductase activity slows down the chromosome replication fork but does not change its localization
   PLoS One, 4 (10), e7617
   PubMed 19898675
4. Waldminghaus T, Skarstad K (2009)
   The Escherichia coli SeqA protein
   Plasmid, 61 (3), 141-50
   PubMed 19254745

Publications 2008

1. Bach T, Morigen, Skarstad K (2008)
   The initiator protein DnaA contributes to keeping new origins inactivated by promoting the presence of hemimethylated DNA
   J Mol Biol, 384 (5), 1076-85
   PubMed 18835566
2. Fossum S, De Pascale G, Weigel C, Messer W, Donadio S, Skarstad K (2008)
   A robust screen for novel antibiotics: specific knockout of the initiator of bacterial DNA replication
   FEMS Microbiol Lett, 281 (2), 210-4
   PubMed 18312360

Publications 2007

1. Fossum S, Crooke E, Skarstad K (2007)
   Organization of sister origins and replisomes during multifork DNA replication in Escherichia coli
   EMBO J, 26 (21), 4514-22
   PubMed 17914458
2. Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K (2007)
   Functional taxonomy of bacterial hyperstructures
   Microbiol Mol Biol Rev, 71 (1), 230-53
   PubMed 17347523
3. Norris V, den Blaauwen T, Doi RH, Harshey RM, Janniere L, Jiménez-Sánchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Misevic G, Ripoll C, Saier M, Skarstad K, Thellier M (2007)
   Toward a hyperstructure taxonomy
   Annu Rev Microbiol, 61, 309-29
   PubMed 17896876

Publications 2006

1. Gon S, Camara JE, Klungsøyr HK, Crooke E, Skarstad K, Beckwith J (2006)
   A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli
   EMBO J, 25 (5), 1137-47
   PubMed 16482221

Publications 2005

1. Bach T, Skarstad K (2005)
   An oriC-like distribution of GATC sites mediates full sequestration of non-origin sequences in Escherichia coli
   J Mol Biol, 350 (1), 7-11
   PubMed 15922360
2. Morigen, Molina F, Skarstad K (2005)
   Deletion of the datA site does not affect once-per-cell-cycle timing but induces rifampin-resistant replication
   J Bacteriol, 187 (12), 3913-20
   PubMed 15939703
3. Odsbu I, Klungsøyr HK, Fossum S, Skarstad K (2005)
   Specific N-terminal interactions of the Escherichia coli SeqA protein are required to form multimers that restrain negative supercoils and form foci
   Genes Cells, 10 (11), 1039-49
   PubMed 16236133

Publications 2004

1. Bach T, Skarstad K (2004)
   Re-replication from non-sequesterable origins generates three-nucleoid cells which divide asymmetrically
   Mol Microbiol, 51 (6), 1589-600
   PubMed 15009887
2. Klungsøyr HK, Skarstad K (2004)
   Positive supercoiling is generated in the presence of Escherichia coli SeqA protein
   Mol Microbiol, 54 (1), 123-31
   PubMed 15458410
3. Molina F, Skarstad K (2004)
   Replication fork and SeqA focus distributions in Escherichia coli suggest a replication hyperstructure dependent on nucleotide metabolism
   Mol Microbiol, 52 (6), 1597-612
   PubMed 15186411

Publications 2003

1. Bach T, Krekling MA, Skarstad K (2003)
   Excess SeqA prolongs sequestration of oriC and delays nucleoid segregation and cell division
   EMBO J, 22 (2), 315-23
   PubMed 12514137
2. Camara JE, Skarstad K, Crooke E (2003)
   Controlled initiation of chromosomal replication in Escherichia coli requires functional Hda protein
   J Bacteriol, 185 (10), 3244-8
   PubMed 12730188
3. Fossum S, Søreide S, Skarstad K (2003)
   Lack of SeqA focus formation, specific DNA binding and proper protein multimerization in the Escherichia coli sequestration mutant seqA2
   Mol Microbiol, 47 (3), 619-32
   PubMed 12535065
4. Kang S, Han JS, Park JH, Skarstad K, Hwang DS (2003)
   SeqA protein stimulates the relaxing and decatenating activities of topoisomerase IV
   J Biol Chem, 278 (49), 48779-85
   PubMed 14512422
5. Miller C, Ingmer H, Thomsen LE, Skarstad K, Cohen SN (2003)
   DpiA binding to the replication origin of Escherichia coli plasmids and chromosomes destabilizes plasmid inheritance and induces the bacterial SOS response
   J Bacteriol, 185 (20), 6025-31
   PubMed 14526013
6. Morigen, Løbner-Olesen A, Skarstad K (2003)
   Titration of the Escherichia coli DnaA protein to excess datA sites causes destabilization of replication forks, delayed replication initiation and delayed cell division
   Mol Microbiol, 50 (1), 349-62
   PubMed 14507385
7. Skarstad K, Boye E, Fanning E (2003)
   Circles in the sand
   EMBO Rep, 4 (7), 661-5
   PubMed 12835752
8. Skarstad K, Løbner-Olesen A (2003)
   Stable co-existence of separate replicons in Escherichia coli is dependent on once-per-cell-cycle initiation
   EMBO J, 22 (1), 140-50
   PubMed 12505992
9. Slominska M, Wahl A, Wegrzyn G, Skarstad K (2003)
   Degradation of mutant initiator protein DnaA204 by proteases ClpP, ClpQ and Lon is prevented when DNA is SeqA-free
   Biochem J, 370 (Pt 3), 867-71
   PubMed 12479794

Publications 2001

1. Morigen, Boye E, Skarstad K, Løbner-Olesen A (2001)
   Regulation of chromosomal replication by DnaA protein availability in Escherichia coli: effects of the datA region
   Biochim Biophys Acta, 1521 (1-3), 73-80
   PubMed 11690638
2. Skarstad K, Torheim N, Wold S, Lurz R, Messer W, Fossum S, Bach T (2001)
   The Escherichia coli SeqA protein binds specifically to two sites in fully and hemimethylated oriC and has the capacity to inhibit DNA replication and affect chromosome topology
   Biochimie, 83 (1), 49-51
   PubMed 11254974
3. Slominska M, Wegrzyn A, Konopa G, Skarstad K, Wegrzyn G (2001)
   SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor
   Mol. Microbiol., 40 (6), 1371-1379
4. Slomi?ska M, Wegrzyn A, Konopa G, Skarstad K, Wegrzyn G (2001)
   SeqA, the Escherichia coli origin sequestration protein, is also a specific transcription factor
   Mol Microbiol, 40 (6), 1371-9
   PubMed 11442835
5. Zheng W, Li Z, Skarstad K, Crooke E (2001)
   Mutations in DnaA protein suppress the growth arrest of acidic phospholipid-deficient Escherichia coli cells
   EMBO J, 20 (5), 1164-72
   PubMed 11230139

Publications 2000

1. Bernander R, Skarstad K (2000)
   Mapping of a chromosome replication origin in an archaeon
   Trends Microbiol, 8 (12), 535-7
   PubMed 11115744
2. Boye E, Løbner-Olesen A, Skarstad K (2000)
   Limiting DNA replication to once and only once
   EMBO Rep, 1 (6), 479-83
   PubMed 11263490
3. Skarstad K, Lueder G, Lurz R, Speck C, Messer W (2000)
   The Escherichia coli SeqA protein binds specifically and co-operatively to two sites in hemimethylated and fully methylated oriC
   Mol Microbiol, 36 (6), 1319-26
   PubMed 10931282
4. Torheim NK, Boye E, Løbner-Olesen A, Stokke T, Skarstad K (2000)
   The Escherichia coli SeqA protein destabilizes mutant DnaA204 protein
   Mol Microbiol, 37 (3), 629-38
   PubMed 10931356

Publications 1999

1. Torheim NK, Skarstad K (1999)
   Escherichia coli SeqA protein affects DNA topology and inhibits open complex formation at oriC
   EMBO J, 18 (17), 4882-8
   PubMed 10469666

Publications 1998

1. Wold S, Boye E, Slater S, Kleckner N, Skarstad K (1998)
   Effects of purified SeqA protein on oriC-dependent DNA replication in vitro
   EMBO J, 17 (14), 4158-65
   PubMed 9670030

Publications 1997

1. Stokke T, Smedshammer L, Jonassen TS, Blomhoff HK, Skarstad K, Steen HB (1997)
   Uncoupling of the order of the S and M phases: effects of staurosporine on human cell cycle kinases
   Cell Prolif, 30 (5), 197-218
   PubMed 9420612

Publications 1996

1. Boye E, Stokke T, Kleckner N, Skarstad K (1996)
   Coordinating DNA replication initiation with cell growth: differential roles for DnaA and SeqA proteins
   Proc Natl Acad Sci U S A, 93 (22), 12206-11
   PubMed 8901558
2. Jair KW, Yu X, Skarstad K, Thöny B, Fujita N, Ishihama A, Wolf RE (1996)
   Transcriptional activation of promoters of the superoxide and multiple antibiotic resistance regulons by Rob, a binding protein of the Escherichia coli origin of chromosomal replication
   J Bacteriol, 178 (9), 2507-13
   PubMed 8626315
3. Wold S, Crooke E, Skarstad K (1996)
   The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro
   Nucleic Acids Res, 24 (18), 3527-32
   PubMed 8836178

Publications 1995

1. Skarstad K, Bernander R, Boye E (1995)
   Analysis of DNA replication in vivo by flow cytometry
   Methods Enzymol, 262, 604-13
   PubMed 8594381
2. Skarstad K, Wold S (1995)
   The speed of the Escherichia coli fork in vivo depends on the DnaB:DnaC ratio
   Mol Microbiol, 17 (5), 825-31
   PubMed 8596432
3. Slater S, Wold S, Lu M, Boye E, Skarstad K, Kleckner N (1995)
   E. coli SeqA protein binds oriC in two different methyl-modulated reactions appropriate to its roles in DNA replication initiation and origin sequestration
   Cell, 82 (6), 927-36
   PubMed 7553853

Publications 1994

1. Skarstad K, Boye E (1994)
   The initiator protein DnaA: evolution, properties and function
   Biochim Biophys Acta, 1217 (2), 111-30
   PubMed 8110826
2. Steen HB, Jernaes MW, Skarstad K, Boye E (1994)
   Staining and measurement of DNA in bacteria
   Methods Cell Biol, 42 Pt B, 477-87
   PubMed 7533253
3. Wold S, Skarstad K, Steen HB, Stokke T, Boye E (1994)
   The initiation mass for DNA replication in Escherichia coli K-12 is dependent on growth rate
   EMBO J, 13 (9), 2097-102
   PubMed 8187762

Publications 1993

1. Skarstad K, Boye E (1993)
   Degradation of individual chromosomes in recA mutants of Escherichia coli
   J Bacteriol, 175 (17), 5505-9
   PubMed 8366035
2. Skarstad K, Thöny B, Hwang DS, Kornberg A (1993)
   A novel binding protein of the origin of the Escherichia coli chromosome
   J Biol Chem, 268 (8), 5365-70
   PubMed 8449900

Publications 1991

1. Crooke E, Hwang DS, Skarstad K, Thöny B, Kornberg A (1991)
   E. coli minichromosome replication: regulation of initiation at oriC
   Res Microbiol, 142 (2-3), 127-30
   PubMed 1925009

Publications 1990

1. Skarstad K, Baker TA, Kornberg A (1990)
   Strand separation required for initiation of replication at the chromosomal origin of E.coli is facilitated by a distant RNA--DNA hybrid
   EMBO J, 9 (7), 2341-8
   PubMed 1694129
2. Steen HB, Skarstad K, Boye E (1990)
   DNA measurements of bacteria
   Methods Cell Biol, 33, 519-26
   PubMed 2084483

Publications 1989

1. Løbner-Olesen A, Skarstad K, Hansen FG, von Meyenburg K, Boye E (1989)
   The DnaA protein determines the initiation mass of Escherichia coli K-12
   Cell, 57 (5), 881-9
   PubMed 2541928
2. Skarstad K, Løbner-Olesen A, Atlung T, von Meyenburg K, Boye E (1989)
   Initiation of DNA replication in Escherichia coli after overproduction of the DnaA protein
   Mol Gen Genet, 218 (1), 50-6
   PubMed 2550764

Publications 1988

1. Boye E, Løbner-Olesen A, Skarstad K (1988)
   Timing of chromosomal replication in Escherichia coli
   Biochim Biophys Acta, 951 (2-3), 359-64
   PubMed 2850013
2. Skarstad K, Boye E (1988)
   Perturbed chromosomal replication in recA mutants of Escherichia coli
   J Bacteriol, 170 (6), 2549-54
   PubMed 3286612
3. Skarstad K, von Meyenburg K, Hansen FG, Boye E (1988)
   Coordination of chromosome replication initiation in Escherichia coli: effects of different dnaA alleles
   J Bacteriol, 170 (2), 852-8
   PubMed 2828328

Publications 1987

1. von Meyenburg K, Boye E, Skarstad K, Koppes L, Kogoma T (1987)
   Mode of initiation of constitutive stable DNA replication in RNase H-defective mutants of Escherichia coli K-12
   J Bacteriol, 169 (6), 2650-8
   PubMed 3034862

Publications 1986

1. Skarstad K, Boye E, Steen HB (1986)
   Timing of initiation of chromosome replication in individual Escherichia coli cells
   EMBO J, 5 (7), 1711-7
   PubMed 3527695
2. Steen HB, Skarstad K, Boye E (1986)
   Flow cytometry of bacteria: cell cycle kinetics and effects of antibiotics
   Ann N Y Acad Sci, 468, 329-38
   PubMed 2942091

Publications 1985

1. Kogoma T, Skarstad K, Boye E, von Meyenburg K, Steen HB (1985)
   RecA protein acts at the initiation of stable DNA replication in rnh mutants of Escherichia coli K-12
   J Bacteriol, 163 (2), 439-44
   PubMed 2991187
2. Skarstad K, Steen HB, Boye E (1985)
   Escherichia coli DNA distributions measured by flow cytometry and compared with theoretical computer simulations
   J Bacteriol, 163 (2), 661-8
   PubMed 3894332

Publications 1984

1. Boye E, Köhnlein W, Skarstad K (1984)
   Characterization of intracellular DNA strand breaks induced by neocarzinostatin in Escherichia coli cells
   Nucleic Acids Res, 12 (21), 8281-91
   PubMed 6239141

Publications 1983

1. Boye E, Steen HB, Skarstad K (1983)
   Flow cytometry of bacteria: a promising tool in experimental and clinical microbiology
   J Gen Microbiol, 129 (4), 973-80
   PubMed 6350534
2. Skarstad K, Steen HB, Boye E (1983)
   Cell cycle parameters of slowly growing Escherichia coli B/r studied by flow cytometry
   J Bacteriol, 154 (2), 656-62
   PubMed 6341358

Publications 1982

1. Steen HB, Boye E, Skarstad K, Bloom B, Godal T, Mustafa S (1982)
   Applications of flow cytometry on bacteria: cell cycle kinetics, drug effects, and quantitation of antibody binding
   Cytometry, 2 (4), 249-57
   PubMed 7035105

Publications 1981

1. Boye E, Alver S, Skarstad K (1981)
   Deoxyribonucleic acid replication in permeable and fully viable Escherichia coli cells
   J Bacteriol, 145 (3), 1413-6
   PubMed 7009586