Llorente/Sandvig publish potential biomarkers for prostate cancer

Llorente (left) and Sandvig

Alicia Llorente and Kirsten Sandvig, Department of Biochemistry, Institute for Cancer Research and Centre for Cancer Biomedicine, have recently published in Molecular and Cellular Proteomics (impact factor 8.4) a proteomic analysis of microvesicles released from a human prostate cancer cell line. Most of the 266 proteins identified have previously been reported to be present in vesicles released from other cell types, but several proteins seem to be specific for prostate cancer cells. Since microvesicles can reach biological fluids, these proteins are thus potentially useful as new non invasive biomarkers for detection, diagnosis and/or prognosis of prostate cancer.

Links

Proteomic analysis of microvesicles released by the human prostate cancer cell line PC-3.
Sandvig K, Llorente A.
Mol Cell Proteomics. 2012 Mar 28. [Epub ahead of print]

Home page of Kirsten Sandvig's group - Intracellular transport

Sandvig's mini CV (including publications)

Department of Biochemistry

Centre for Cancer Biomedicine

Recent publications

From major journals, first or last author from the Institute for Cancer Research

Skourti E, Seip K, Mensali N, Jabeen S, Juell S, Øynebråten I, Pettersen S, Engebraaten O, Corthay A, Inderberg EM, Dolznig H, Mælandsmo GM, Egeland EV, Prasmickaite L (2025)
Chemoresistant tumor cell secretome potentiates immune suppression in triple negative breast cancer
Breast Cancer Res, 27 (1), 131
DOI 10.1186/s13058-025-02082-x, PubMed 40660361

Lystad AH (2025)
V-ATPase assembly at leaky lysosomes
Nat Struct Mol Biol (in press)
DOI 10.1038/s41594-025-01612-7, PubMed 40646311

Patel D, Tiusanen V, Karttunen K, Pihlajamaa P, Sahu B (2025)
Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes
Commun Biol, 8 (1), 992
DOI 10.1038/s42003-025-08413-0, PubMed 40610675

More selected publications

Most recent publications

Chen Y, He L, Ianevski A, Nader K, Ruokoranta T, Linnavirta N, Miettinen JJ, Vähä-Koskela M, Vänttinen I, Kuusanmäki H, Kontro M, Porkka K, Wennerberg K, Heckman CA, Giri AK, Aittokallio T (2025)
A Machine Learning-Based Strategy Predicts Selective and Synergistic Drug Combinations for Relapsed Acute Myeloid Leukemia
Cancer Res, 85 (14), 2753-2768
DOI 10.1158/0008-5472.CAN-24-3840, PubMed 40354625

Skourti E, Seip K, Mensali N, Jabeen S, Juell S, Øynebråten I, Pettersen S, Engebraaten O, Corthay A, Inderberg EM, Dolznig H, Mælandsmo GM, Egeland EV, Prasmickaite L (2025)
Chemoresistant tumor cell secretome potentiates immune suppression in triple negative breast cancer
Breast Cancer Res, 27 (1), 131
DOI 10.1186/s13058-025-02082-x, PubMed 40660361

Lystad AH (2025)
V-ATPase assembly at leaky lysosomes
Nat Struct Mol Biol (in press)
DOI 10.1038/s41594-025-01612-7, PubMed 40646311

More publications

Annual summary of publications