Group leader in cancer informatics

Responsible for cross-group cancer informatics. Implementation of computational infrastructure and bioinformatics pipelines. Researcher in cancer heterogeneity, pan-cancer. Primarily research on prostate, colorectal, and ovarian cancers.


Education

MSc in Mathematical modeling, Dept of Informatics, University of Oslo, Norway (2000)

MSc in Biochemistry, Dept of Molecular Biosciences, University of Oslo, Norway (2011)

PhD in Cancer Genomics, Faculty of Medicine, University of Oslo, Norway (2016)


Research interests

My current research interests involve analysis of different types of large scale genomic data from high-throughput methodologies:

– Algorithms for identification of mutations in solid cancers

– DNA/RNA sequencing analysis

– Cancer biomarker detection


Projects

The Norwegian Cancer Genomics Consortium (www.kreftgenomikk.no)

Recent collaborative projects I have been co-authoring:

Sveen*, Johannessen*, Tengs* et al., Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1, Genome Medicine (2017)

Løvf et al., Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity, European Urology (2018)

Wise et al., Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series, Blood Advances (2020)

Sveen, Johannessen et al., The expressed mutational landscape of microsatellite stable colorectal cancers, Genome Med (2021)

Popular scientific communication

Johannessen, Strømme, Skotheim, The quest for biomarkers in prostate cancer: Multi-sample transcriptomics overcomes heterogeneity and reveals genes with prognostic biomarker potential, Nature Portfolio Communities (2022)

Johannessen, Berg, Bruk av udødelige cellelinjer på tarmkreft, Best Practice (2017)

Johannessen, Skotheim, From numbers and sequences to personalized cancer treatment: Challenges and opportunities as medicine enters the era of big data, Meta Magazine (2015)