Alfonso Urbanucci

  • Principal investigator; PhD

Bio :

Dr. Urbanucci graduated from the University of Perugia, Italy, in biology with a specialization in pathophysiology, and obtained his Ph.D. in cancer genetics and molecular biology of cancer at the University of Tampere , Finland, in 2012. His personal research interest is on the transcriptional and chromatin drivers underpinning prostate cancer progression , with the androgen receptor as a focal point. He published a series of papers regarding the molecular effects of the deregulation of the androgen receptor on chromatin and transcription, and how these effects drive prostate cancer progression.

Dr. Urbanucci is currently Project Group Leader at the Institute for Cancer Research of the Oslo University Hospital, and associate investigator at the Center for Molecular Medicine Norway (European Molecular Biology Laboratory partnership) .

His research group investigates molecular mechanisms of action of small molecule inhibitors and derives novel prognostic and predictive tools for patient stratification.

Dr Urbanucci is also Group Leader and principal investigator at the Faculty of Medicine and Health Technology (University of Tampere).

The focus of the research is on dissecting prostate cancer dependencies at a single cell level for tailored treatments. We aim to retrieve cell composition from bulk tissue gene expression data and prognostic and predictive gene signatures associated with aggressive vs non-lethal tumor behaviour.